Osteoplastic surgery of the face—state of the art and future aspects

Vinzenz, K.; Schaudy, C.

doi:10.1007/s12548-011-0028-1

Cited by 3 publications

(1 citation statement)

References 95 publications

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“…To date the most frequently used technique for reconstruction of extended defects is the transfer of vascularized osseous respectively osseo(-myo-)cutaneous free flaps in particular as part of oncologic surgery of the head and neck region. Fibula, scapula, and iliac crest were the preferred donor sites ( Vinzenz and C. Schaudy, 2011 ).…”

Section: Introductionmentioning

confidence: 99%

Translational Research: Palatal-derived Ecto-mesenchymal Stem Cells from Human Palate: A New Hope for Alveolar Bone and Cranio-Facial Bone Reconstruction

Grimm¹,

Dannan²,

Giesenhagen³

et al. 2014

Int J Stem Cells

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The management of facial defects has rapidly changed in the last decade. Functional and esthetic requirements have steadily increased along with the refinements of surgery. In the case of advanced atrophy or jaw defects, extensive horizontal and vertical bone augmentation is often unavoidable to enable patients to be fitted with implants. Loss of vertical alveolar bone height is the most common cause for a non primary stability of dental implants in adults. At present, there is no ideal therapeutic approach to cure loss of vertical alveolar bone height and achieve optimal pre-implantological bone regeneration before dental implant placement. Recently, it has been found that specific populations of stem cells and/or progenitor cells could be isolated from different dental resources, namely the dental follicle, the dental pulp and the periodontal ligament. Our research group has cultured palatal-derived stem cells (paldSCs) as dentospheres and further differentiated into various cells of the neuronal and osteogenic lineage, thereby demonstrating their stem cell state. In this publication will be shown whether paldSCs could be differentiated into the osteogenic lineage and, if so, whether these cells are able to regenerate alveolar bone tissue in vivo in an athymic rat model. Furthermore, using these data we have started a proof of principle clinical- and histological controlled study using stem cell-rich palatal tissues for improving the vertical alveolar bone augmentation in critical size defects. The initial results of the study demonstrate the feasibility of using stem cell-mediated tissue engineering to treat alveolar bone defects in humans.

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Section: Introductionmentioning

confidence: 99%

Translational Research: Palatal-derived Ecto-mesenchymal Stem Cells from Human Palate: A New Hope for Alveolar Bone and Cranio-Facial Bone Reconstruction

Grimm¹,

Dannan²,

Giesenhagen³

et al. 2014

Int J Stem Cells

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The Management of Patients after Surgical Treatment of Maxillofacial Tumors

Rolski

Kostrzewa-Janicka

Zawadzki

et al. 2016

BioMed Research International

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Morphological and functional disturbances induced by postsurgical defects and loss of tissues in the stomatognathic system due to the treatment of tumors in the maxillofacial region determine the therapeutic needs of patients. The study aimed at clinical and epidemiological evaluation of patients under prosthetic treatment in order to establish the algorithm for rehabilitation. The study group was composed of the patients after midface surgery (45.74%); surgery in a lower part of the face (47.38%); mixed postoperative losses (3.44%); loss of face tissues and surgery in other locations in the head and neck region (3.44%). The supplementary treatment was applied in 69.63% of patients. Clinical and additional examinations were performed to obtain the picture of postoperative loss, its magnitude, and location to plan the strategy of prosthetic rehabilitation. The management algorithm for prosthetic rehabilitation in patients after surgical treatment of maxillofacial neoplasms was based on its division in stages. The location and magnitude of postoperative losses, as well as the implementation of supplementary treatment of the patients after treatment of maxillofacial tumors, influence the planning of prosthetic rehabilitation that plays a key role and facilitates the patients' return to their prior living situation, occupational and family lives.

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Mandibular Reconstruction and Rehabilitation with Vascularized Free Fibula Flap with Further Endosteal Implants

Khachatryan

Khachatryan²,

Hovhannisyan

et al. 2022

JBSMFS

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Objectives:To evaluate of the effectiveness of rehabilitation in patients following mandibulectomy and free fibula flap reconstruction with further endosteal implants. Materials and Metods: The patient cohort consisted of 27 patients years (14 males and 13 females) with lower jaw defects due to resection for tumors, were reconstructed with fibula-free flaps in a 6-year period (2015-2020). All patients underwent a thorough clinical laboratory, radiological examination according to a generally accepted scheme. Patients were evaluated by preoperative and postoperative outcome using computed tomography scan evaluation. The surgical procedure included: Segmentar resection of the lower jaw, reconstruction with fibula free flap. The implants were evaluated with measures of Resonance Frequency Analysis (RFA) during the follow-up periods using Osstell Mentor at time of implant placement, after 3 months. The mean RFA recordings of all 134 implants were 65 ISQ at implant placement respectively 73 ISQ after 3 months. After 4-6 months of healing, 152 dental implants were placed in non-irradiated fibular bone. Dental prosthetic rehabilitation was performed after 3-4 months of submerged healing. Patients had received implant-bridge and hybrid denture that provided ideal facial balance and occlusion. Results:Postoperative clinical and radiographic controls were made regularly, the criteria for implant success were assessed.With dynamic observation, clinical and radiological indices were stable, of the 152 implants installed, 2 failed to osseointegrate and 5 after years of loading (peri-implantitis). Success rate of implants 5 years after was 96.1%. Conclusion:The reconstruction of the lower jaw defects after ablation of tumors with fibular flaps is a reliable method with good long-term results. In all 27 patients, fibula flaps provided adequate bone stock for implant placement. Implants placed in the reconstructed areas were demonstrated to integrate normally. The results showed that implant treatment is effective to improve patients‘ masticatory efficiency and an acceptable quality of life to the patient

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Osteoplastic surgery of the face—state of the art and future aspects

Cited by 3 publications

References 95 publications

Translational Research: Palatal-derived Ecto-mesenchymal Stem Cells from Human Palate: A New Hope for Alveolar Bone and Cranio-Facial Bone Reconstruction

Translational Research: Palatal-derived Ecto-mesenchymal Stem Cells from Human Palate: A New Hope for Alveolar Bone and Cranio-Facial Bone Reconstruction

The Management of Patients after Surgical Treatment of Maxillofacial Tumors

Mandibular Reconstruction and Rehabilitation with Vascularized Free Fibula Flap with Further Endosteal Implants

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