Osteoporosis and Bone Health

Nutrient element-based bioceramic coatings on titanium alloy stimulating osteogenesis by inducing beneficial osteoimmmunomodulation

“…ALP, OPN and COL1 are early markers of the osteoblast lineage while OCN is thought to be pinpointing of a more mature osteoblastic phenotype. 57 Therefore, it is reasonable to observe that ALP, OPN and COL1 were upregulated in the early stage (day 3), while OCN was upregulated only in the late stage (day 7). The osteogenic effects may be related to the upregulation of BMP2 and VEGF.…”

Experimental investigation of bone mineral density in Thoroughbreds using quantitative computed tomography

“…In this study, male horses and female horses showed similar changes with age; in other words, female horses did not show a dramatic decrease in BMD with age. However, horses have a reproduction period during their entire lives that differs from that of humans [ 8 ]. As isolated legs were used in this experiment, serum was not collected.…”

“…In humans, bone mineral density (BMD) is considered an important health indication because it allows clinicians to evaluate the risk of fracture [ 8 , 14 ]. It is well known that athletes who engage in high-impact sports tend to have higher BMD values than athletes who engage in low-impact sports, and fatigue fractures are seen frequently in low-impact sport athletes, particularly runners [ 16 , 24 ].…”

Magnetic Resonance Imaging Tracking of Stem Cells in Vivo Using Iron Oxide Nanoparticles as a Tool for the Advancement of Clinical Regenerative Medicine

“…As a result, angiogenesis stimulates host progenitors to repair the damaged site. Therefore, there is an increasing interest in culture-expanded MSCs as a promising cell source for clinical use such as regeneration of bone defects, , spinal cord injury, stroke, and myocardial infarction . In vivo animal tests have already proved the ability of the MSCs to repair large full-thickness defects in the formal condyle .…”