Osteoporosis in primary biliary cirrhosis of the liver

Raszeja‐Wyszomirska, Joanna; Miazgowski, Tomasz

doi:10.5114/pg.2014.42502

Cited by 25 publications

(33 citation statements)

References 34 publications

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“…One of the reasons for the scarcity of reported cases is the low prevalence of PSC itself, which ranges from 4 to 16/million [44]. In contrast, the reported prevalence of PBC is 19-402/million [34,35,49]. It remains unclear whether SLE with concomitant PSC occurs by chance or these entities have a common immunological basis.…”

Section: Psc In Patients With Slementioning

confidence: 86%

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Liver Complications Associated with Systemic Lupus Erythematosus

Shizuma

2015

Rheumatology (Sunnyvale)

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Although liver dysfunction is not considered the main organ pathology or prognostic factor in patients with Systemic Lupus Erythematosus (SLE), it is not uncommon during the course of SLE. Liver complications in patients with SLE may be caused by lupus hepatitis (SLE-related hepatitis); autoimmune liver diseases, such as Autoimmune Hepatitis (AIH) and Primary Biliary Cirrhosis (PBC); viral hepatitis; and drug-induced liver injury. Here, liver complications in patients with SLE are reviewed.

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Section: Psc In Patients With Slementioning

confidence: 86%

“…Prognosis is often dependent on the development of portal hypertension or LC. Furthermore, patients with end-stage liver failure require an organ transplant [35]. In such cases, prognostic models such as the Mayo risk score and bilirubin levels are useful for determining the optimal timings for the liver transplantation [36].…”

Section: Pbc In Patients With Slementioning

confidence: 99%

Liver Complications Associated with Systemic Lupus Erythematosus

Shizuma

2015

Rheumatology (Sunnyvale)

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“…Its incidence is estimated to be 5/100.000 persons/year, while the prevalence is 50-250/ 1.000.000 (24). Osteoporosis is a frequent complication of PBC, mostly in the advanced stages of PBC (25).…”

Section: Primary Biliary Cirrhosismentioning

confidence: 99%

Rare causes of osteoporosis

Marcucci

Brandi

2015

ccmbm

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SummaryOsteoporosis is a metabolic bone disease characterized by loss of bone mass and strength, resulting in increased risk of fractures. It is classically divided into primary (postmenopausal or senile), secondary and idiopathic forms. There are many rare diseases, that cause directly or indirectly osteoporosis. The identification and classification of most of these rare causes of osteoporosis is crucial for the specialists in endocrinology and not, in order to prevent this bone complication and to provide for an early therapy. Several pathogenic mechanisms are involved, including various aspects of bone metabolism such as: decreased bone formation, increased bone resorption, altered calcium, phosphorus and/or vitamin D homeostasis, and abnormal collagen synthesis. In this review, less common forms of primary and secondary osteoporosis are described, specifying, if applicable: genetic causes, epidemiology, clinical features, and pathogenic mechanisms causing osteoporosis. A greater awareness of all rare causes of osteoporosis could reduce the number of cases classified as idiopathic osteoporosis and allow the introduction of appropriate and timely treatments.

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“…Disease progression can be significantly inhibited by treatment with ursodeoxycholic acid (UDCA) in some cases [14,17]; however, patients with end-stage liver failure require organ transplantation [16].…”

Section: Pbcmentioning

confidence: 99%

“…PBC affects middleaged women (women in their fifth or sixth decade) more often than men (ratio of 9-10:1) [15,16].…”

Section: Pbcmentioning

confidence: 99%

A Literature Review of Concomitant Primary Biliary Cirrhosis and GravesÂ’ Disease

Shizuma¹

2015

J Gastrointest Dig Syst

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Although Hashimoto's thyroiditis (HT) is commonly characterized by extrahepatic manifestations of primary biliary cirrhosis (PBC), coexistence of PBC and Graves' disease (GD) is uncommon. This is a review of the English and Japanese scientific literature, comprising 7 cases of PBC and GD coexistence. All patients were female. In 4 cases, both diseases were almost simultaneously diagnosed, whereas PBC preceded GD in the remaining 3 cases. One fatality was observed on account of sepsis and liver failure caused by progressing PBC.

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Osteoporosis in primary biliary cirrhosis of the liver

Cited by 25 publications

References 34 publications

Liver Complications Associated with Systemic Lupus Erythematosus

Liver Complications Associated with Systemic Lupus Erythematosus

Rare causes of osteoporosis

A Literature Review of Concomitant Primary Biliary Cirrhosis and GravesÂ’ Disease

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