Otoacoustic emission suppression in children diagnosed with central auditory processing disorder and speech in noise perception deficits

Iliadou, Vasiliki Vivian; Weihing, Jeffrey; Chermak, Gail D.; Bamiou, Doris‐Eva

doi:10.1016/j.ijporl.2018.05.027

Cited by 13 publications

(12 citation statements)

References 48 publications

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“…Asymmetry between right and left ears is not uncommon and it is found in different audiometric tests (McFadden, 1993; Khalfa and Collet, 1996; Khalfa et al, 1997; Veuillet et al, 2007; DeLeon et al, 2012). Correlation of OAE suppression and SinB failure in APD diagnosed children has been recently documented (Iliadou et al, 2018d) indicating a possible lesion at the level of the brainstem and beyond.…”

Section: Discussionmentioning

confidence: 93%

Deficits in Auditory Rhythm Perception in Children With Auditory Processing Disorder Are Unrelated to Attention

et al. 2019

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Auditory processing disorder (APD) is defined as a specific deficit in the processing of auditory information along the central auditory nervous system, including bottom-up and top-down neural connectivity. Even though music comprises a big part of audition, testing music perception in APD population has not yet gained wide attention in research. This work tests the hypothesis that deficits in rhythm perception occur in a group of subjects with APD. The primary focus of this study is to measure perception of a simple auditory rhythm, i.e., short isochronous sequences of beats, in APD children and to compare their performance to age-matched normal controls. The secondary question is to study the relationship between cognition and auditory processing of rhythm perception. We tested 39 APD children and 25 control children aged between 6 and 12 years via (a) clinical APD tests, including a monaural speech in noise test, (b) isochrony task, a test measuring the detection of small deviations from perfect isochrony in a isochronous beats sequence, and (c) two cognitive tests (auditory memory and auditory attention). APD children scored worse in isochrony task compared to the age-matched control group. In the APD group, neither measure of cognition (attention nor memory) correlated with performance in isochrony task. Left (but not right) speech in noise performance correlated with performance in isochrony task. In the control group a large correlation (r = −0.701, p = 0.001) was observed between isochrony task and attention, but not with memory. The results demonstrate a deficit in the perception of regularly timed sequences in APD that is relevant to the perception of speech in noise, a ubiquitous complaint in this condition. Our results suggest (a) the existence of a non-attention related rhythm perception deficit in APD children and (b) differential effects of attention on task performance in normal vs. APD children. The potential beneficial use of music/rhythm training for rehabilitation purposes in APD children would need to be explored.

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Section: Discussionmentioning

confidence: 93%

Deficits in Auditory Rhythm Perception in Children With Auditory Processing Disorder Are Unrelated to Attention

et al. 2019

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“…Muchnik et al (2004) reported a significant group difference in a slightly shorter and later time window (8-20 ms) but not when the entire CEOAE duration was (2.5-20 ms) was considered. Iliadou et al (2018) performed an overlapping (1 ms-moving window) temporal analysis; however, they did not report on group differences (high vs. low scorers in a speech-in-noise test) or the actual post-stimulus time of their time windows. Garinis et al (2008) reported marked enhancement in their study group (learning disability) in the 12 to 14 ms window.…”

Section: Within-and Across-epoch Temporal Analysis Of Ceoae Lateralities Do Not Support a Compromised Mocr In The Lid Groupmentioning

confidence: 99%

The Medial Olivocochlear Reflex Is Unlikely to Play a Role in Listening Difficulties in Children

et al. 2019

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The medial olivocochlear reflex (MOCR) has been implicated in several auditory processes. The putative role of the MOCR in improving speech perception in noise is particularly relevant for children who complain of listening difficulties (LiD). The hypothesis that the MOCR may be impaired in individuals with LiD or auditory processing disorder has led to several investigations but without consensus. In two related studies, we compared the MOCR functioning of children with LiD and typically developing (TD) children in the same age range (7–17 years). In Study 1, we investigated ipsilateral, contralateral, and bilateral MOCR using forward-masked click-evoked otoacoustic emissions (CEOAEs; n = 17 TD, 17 LiD). In Study 2, we employed three OAE types: CEOAEs ( n = 16 TD, 21 LiD), stimulus frequency OAEs ( n = 21 TD, 30 LiD), and distortion product OAEs ( n = 17 TD, 22 LiD) in a contralateral noise paradigm. Results from both studies suggest that the MOCR functioning is not significantly different between the two groups. Some likely reasons for differences in findings among published studies could stem from the lack of strict data quality measures (e.g., high signal-to-noise ratio, control for the middle ear muscle reflex) that were enforced in the present study. The inherent variability of the MOCR, the subpar reliability of current MOCR methods, and the heterogeneity in auditory processing deficits that underlie auditory processing disorder make detecting clinically relevant differences in MOCR function impractical using current methods.

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“…Several different studies have reported that speech is a multisensory process in which auditory perception plays a key role [48–51]. Additionally, some studies have reported that MSD patients are more likely to suffer more from perceptual disorder; however, the elaborate relationship and mechanism involved in PD-associated perceptual problems are unknown [52–54]. In the present study, univariate analysis showed a greater burden of perceptual problems in the MSD group than in the non-MSD group, but multivariate logistic regression analysis excluded perceptual problems as an independent risk factor for PD-associated MSD.…”

Section: Discussionmentioning

confidence: 99%

Attention/memory complaint is correlated with motor speech disorder in Parkinson’s disease

Liu

Gui

et al. 2019

BMC Neurol

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BackgroundThe mechanisms underlying the online modulation of motor speech in Parkinson’s disease (PD) have not been determined. Moreover, medical and rehabilitation interventions for PD-associated motor speech disorder (MSD) have a poor long-term prognosis.MethodsTo compare risk factors in PD patients with MSD to those without MSD (non-MSD) and determine predictive independent risk factors correlated with the MSD phenotype, we enrolled 314 PD patients, including 250 with and 64 without MSD. We compared demographic, characteristic data, as well as PD-associated evaluations between the MSD group and non-MSD group.ResultsUnivariate analysis showed that demographic characteristics, including occupation, educational level, monthly income and speaking background; clinical characteristics, including lesions in the frontal and temporal lobes, and concurrent dysphagia; and PD-associated evaluations, including the activity of daily living (ADL) score, non-motor symptoms scale (NMSS) domain 4 score (perceptual problem), and NMSS domain 5 score (attention/memory) were all significantly different between the MSD and non-MSD group (all P < 0.05). Multivariate logistic regression analysis showed that educational level, frontal lesions, and NMSS domain 5 score (attention/memory) were independent risk factors for PD-associated MSD (all P < 0.005).ConclusionsWe determined an association between MSD phenotype and cognitive impairment, reflected by low-level education and related clinical profiles. Moreover, attention and memory dysfunction may play key roles in the progression of MSD in PD patients. Further studies are required to detail the mechanism underlying abnormal speech motor modulation in PD patients. Early cognitive intervention may enhance rehabilitation management and motor speech function in patients with PD-associated MSD.

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Otoacoustic emission suppression in children diagnosed with central auditory processing disorder and speech in noise perception deficits

Abstract: Results indicate that suppression is influenced by the time window analysed, and ear tested, and is associated with speech recognition in babble performance in children with central auditory processing disorder.

Cited by 13 publications

References 48 publications

Deficits in Auditory Rhythm Perception in Children With Auditory Processing Disorder Are Unrelated to Attention

Deficits in Auditory Rhythm Perception in Children With Auditory Processing Disorder Are Unrelated to Attention

The Medial Olivocochlear Reflex Is Unlikely to Play a Role in Listening Difficulties in Children

Attention/memory complaint is correlated with motor speech disorder in Parkinson’s disease

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