Otologic findings in children with gastroesophageal reflux

Sleep quality and communication aspects in children

“…It should be emphasized that sleep evaluation in a previous study [13] was performed through polysomnography, which was a limitation of the procedures used in the present study. In addition, it should be emphasized that auditory alterations may be related to the history of chronic middle otitis frequently observed newborns with physiologic gastroesophageal reflux, which is related to obstructive sleep disorders [29].…”

Variations in Definitions and Outcome Measures in Gastroesophageal Reflux Disease: A Systematic Review

“…Ostrom et al 26 Tolia et al 27 Ummarino et al 28 Van Eygen and Van Ravensteyn 29 Vandenplas et al 30 Vanderhoof et al 31 Xinias et al 32 Buts et al 33 Carroccio et al 34 Cohen et al 35 Cucchiara et al 36 Forbes et al 37 Greally et al 38 Levi et al 39 Levy et al, 40 Scott et al 41 Serra et al 42 Clinical Surprisingly, between studies, the same parameters and cutoff values for interpretation were used by authors in their definitions of both GER and GERD. This finding importantly indicates that between studies, terminology may be used interchangeably and patients with similar clinical characteristics may as well be attributed physiologic GER or pathologic GERD.…”

“…Ravensteyn 29 Vandenplas et al 30 Vanderhoof et al 31 Xinias et al 32 Buts et al 33 Carroccio et al 34 Cohen et al 35 Cucchiara et al 36 Forbes et al 37 Greally et al 38 Levi et al 39 Levy et al 40 Orenstein et al 59 Scott et al 41 Serra et al 42 Clinical parameters (n = 23 different primary outcomes) 54 Cucchiara et al 55 Gustafsson et al 56 Oderda et al 57 Omari et al 58 Orenstein et al 59 Simeone b , 60 Ummarino et al 61 different signs and symptoms accordingly. In addition to establishing a minimum core outcome set, establishing sets of proposed secondary outcome measures, depending on the object of the study as well as on the study population may well be appropriate.…”

Prevalence of broncopulmonary and otorhinolaryngologic symptoms in children under investigation for gastroesophageal reflux disease: retrospective analysis

“…However, animal models and human studies, have suggested that the LES muscle is not weaker than in the adult, nonetheless, there is an inadequate relaxation of this muscle, since its maturing will only happen at around 3 months of age, when the LES which was intra-thoracic, starts having an intra-abdominal portion 3 . It is very common, especially in children, besides the classic pyrosis, seeing manifestations in the upper and lower airways [4][5][6][7][8][9] . Among them, we can mention recurrent tonsillitis, recurrent pharyngotonsillitis, asthma, recurrent otitis media, and others [5][6][7] .…”