Otologic Manifestations of Fatal Granulomatosis of Respiratory Tract: Lethal Midline Granuloma-- Wegener's Granulomatosis

Blatt, Irving M.; Lawrence, Merle

doi:10.1001/archotol.1961.00740020653003

Cited by 48 publications

(13 citation statements)

References 11 publications

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“…Occasionally the otological manifestation may be the first and only sign of Wegener's Granulomatosis (McCaffrey et al, 1980;Per-Lee and Parsons, 1969;Blatt and Lawrence, 1961). This is a case report of Wegener's Granulomatosis in a young man who had bilateral otitis media associated with a facial palsy, followed by a discussion of the difficulties encountered in making the correct diagnosis.…”

Section: Introductionmentioning

confidence: 91%

Wegener's Granulomatosis of the ear

Bradley¹

1983

J. Laryngol. Otol.

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Section: Introductionmentioning

confidence: 91%

Wegener's Granulomatosis of the ear

Bradley¹

1983

J. Laryngol. Otol.

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“…Wegener's disease). 14 These changes in the inner ear could be considered to be due to compromised arterial supply to the temporal bone secondary to PAN, resulting in diffuse or focal areas of ischaemic necrosis. 15 Studies by Jenkins et al, 9 Gussen 10 and Yoon et al 11 showed that the internal auditory artery and its branch subarcuate artery were involved, confirming the presence of small vessel disease of the inner ear.…”

Section: Discussionmentioning

confidence: 99%

Polyarteritis nodosa and cochlear implantation

2006

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Polyarteritis nodosa is a systemic disease which affects the small to medium-sized muscular arteries. Sudden or progressive, bilateral hearing loss is a presenting otologic manifestation. To date, no case of cochlear implantation in patients with polyarteritis nodosa has been reported. The authors present a case of polyarteritis nodosa (confirmed by biopsy) in a 71-year-old man with progressive, bilateral sensorineural hearing loss who underwent cochlear implantation. A successful full insertion of the Nucleus 3G electrode array was achieved without surgical or post-operative complications. The patient immediately showed a positive subjective response and, at three month post-operative evaluation, had gained useful open-set speech perception. A review of five temporal bone cases with hearing loss and polyarteritis nodosa revealed the possibility of fibrosis and ossification in the basal turn of the cochlea, of which the surgeon should be aware prior to cochlear implantation.

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“…This finding is usually associated with a conductive hearing loss [ 1,13]. In 1971 Cody [5] first reported a severe bilateral sensorineural impairment in a 69-year-old man with Wegener's granulo matosis, which was improved, like some re ported cases of Cogan's disease [ 16], by ther apy with prednisone.…”

Section: Discussionmentioning

confidence: 99%

Wegener’s Granulomatosis with Otological Disorders as Primary Symptoms

Guyot¹,

Baud²,

Montandon³

1990

ORL

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Otological symptoms as initial manifestations of Wegener’s granulomatosis have been observed in 3 patients. In one of them, symptoms consisted of a bilateral sensorineural hearing loss, improved by corticoid therapy. No other organ system was involved and laboratory tests remained within normal limits for 2 years after the onset of otological signs. In the other 2 patients, Wegener’s granulomatosis manifested mainly as serous otitis media. Otologic involvement underscores the role of the otolaryngologist in the early diagnosis and treatment of this disease.

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Otologic Manifestations of Fatal Granulomatosis of Respiratory Tract: Lethal Midline Granuloma-- Wegener's Granulomatosis

Cited by 48 publications

References 11 publications

Wegener's Granulomatosis of the ear

Wegener's Granulomatosis of the ear

Polyarteritis nodosa and cochlear implantation

Wegener’s Granulomatosis with Otological Disorders as Primary Symptoms

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