Otosclerosis

Redfors, Ylva Dahlin; Gröndahl, Hans Göran; Hellgren, Johan; Lindfors, Ninita; Nilsson, Inger; Möller, Claes

doi:10.1097/mao.0b013e318259b38c

Cited by 33 publications

(3 citation statements)

References 20 publications

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“…In another study, two types of heterotopic mineralization (ossification, including abaxial avulsion fracture of the proximal sesamoid bones, and ligament and tendon mineralization) were reliably detected using CBCT imaging of the equine fetlock region ( 25 ). Likewise, the general suitability of CBCT imaging for the diagnostic assessment of bony structures and bone-related pathologies has been shown by numerous comparative studies on human skeletal structures ( 29 , 30 ). Using clinically applied protocols, both CBCT and MDCT imaging produced diagnostic images for the assessment of the human pelvis, head, and neck.…”

Section: Discussionmentioning

confidence: 99%

Visualization of anatomical structures in the fetlock region of the horse using cone beam computed tomography in comparison with conventional multidetector computed tomography

Bierau,

Cruz,

Koch

et al. 2024

Front. Vet. Sci.

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IntroductionCone-beam computed tomography (CBCT) is regarded as a convenient and suitable alternative to conventional computed tomography. However, in the horse, the quality of obtained data sets needs to be evaluated. Therefore, the aim of this study was to compare the visibility and accessibility of clinically relevant anatomical structures displayed in CBCT and conventional multidetector computed tomography (MDCT).Materials and methodsTwenty-nine limbs from horses euthanized for reasons unrelated to this study were used. Native and intraarticular contrast scans of the fetlock (CBCT vs. MDCT) were performed. The visibility and accessibility of selected anatomical structures were blindly scored by three independent experienced observers using a scoring system previously reported and adapted to the fetlock joint.ResultsOnly minor differences between CBCT and MDCT were identified concerning the diagnostic quality of images for osseous structures. Soft tissue structures were better evaluated on MDCT images. In CBCT as well as in MDCT articular cartilage could only be visualized after intraarticular injection of contrast medium.Discussion/conclusionCone beam computed tomography of the fetlock is a useful and reliable diagnostic tool when evaluating osseous structures and delineating articular cartilage with contrast medium. However, this modality is limited for assessing soft tissues structures.

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Section: Discussionmentioning

confidence: 99%

Visualization of anatomical structures in the fetlock region of the horse using cone beam computed tomography in comparison with conventional multidetector computed tomography

Bierau,

Cruz,

Koch

et al. 2024

Front. Vet. Sci.

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“…Notably, CBCT showed a sensitivity of 100% in cases of active otosclerosis but dropped to 0% in cases of inactive otosclerosis [ 20 ]. Another study by Redfors et al found that HRCT had higher sensitivity than CBCT, specifically for fenestral otosclerotic lesions [ 21 ]. The U-HRCT device in this study is designed based on the principle of CBCT, and the acquisition layer thickness was 0.1 mm.…”

Section: Discussionmentioning

confidence: 99%

Comparative study of the sensitivity of ultra-high-resolution CT and high-resolution CT in the diagnosis of isolated fenestral otosclerosis

Xu,

Ding,

Tang

et al. 2023

Insights Imaging

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Purpose To compare the diagnostic sensitivity of ultra-high-resolution computed tomography (U-HRCT) and HRCT in isolated fenestral otosclerosis (IFO). Methods A retrospective analysis was conducted on 85 patients (85 ears) diagnosed with IFO between October 2020 and November 2022. U-HRCT (0.1 mm thickness) was performed for 20 ears, HRCT (0.67 mm thickness) for 45 ears, and both for 20 ears. The images were evaluated by general radiologists and neuroradiologists who were blinded to the diagnosis and surgical information. The diagnostic sensitivity of U-HRCT and HRCT for detecting IFO was compared between the two groups. Results Excellent inter-observer agreement existed between the two neuroradiologists (Cohen’s κ coefficient 0.806, 95% CI 0.692–0.920), with good agreement between the general radiologists (Cohen’s κ coefficient 0.680, 95% CI 0.417–0.943). U-HRCT had a sensitivity of 100% (40/40 ears) for neuroradiologists and 87.5% (35/40 ears) for general radiologists, significantly higher than HRCT (89.2% [58/65 ears] for neuroradiologists; 41.5% [27/65 ears] for general radiologists) (p = 0.042, p′ < 0.000). General radiologists’ sensitivity with HRCT was significantly lower compared to neuroradiologists (p < 0.000), but no significant difference was observed when general radiologists switched to U-HRCT (p = 0.152). Among the 20 ears that underwent both examinations, U-HRCT detected lesions smaller than 1 mm in 5 ears, whereas HRCT’s sensitivity for neuroradiologists was 40% (2/5 ears), significantly lower than for lesions larger than 1 mm (93.3%, 14/15 ears, p = 0.032). Conclusion U-HRCT exhibits higher sensitivity than HRCT in diagnosing IFO, suggesting its potential as a screening tool for suspected otosclerosis patients. Critical relevance statement Ultra-high-resolution computed tomography has the potential to become a screening tool in patients with suspected otosclerosis and to bridge the diagnostic accuracy gap between general radiologists and neuroradiologists. Key points • U-HRCT exhibits higher sensitivity than HRCT in the diagnosis of IFO. • U-HRCT has a significant advantage in the detection of less than 1 mm IFO. • U-HRCT has the potential to be used for screening of patients with suspected otosclerosis. Graphical Abstract

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“…Furthermore, it was found in several studies that the invasion of the cochlear endoste by the otosclerotic foci on CT is correlated with a poor prognosis [4] [10] [16] [17]. Indeed, this phenomenon leads to a release of enzymes in the labyrinthine fluid, causing inflammation and degeneration of intra-cochlear structures, which can lead to severe sensorineural hearing loss [4] [18]- [20].…”

Section: Discussionmentioning

confidence: 99%

Otosclerosis: Contribution of Computed Tomography and Radio-Anatomical Correlations

Khamassi¹,

Mahfoudhi²,

Mbarek³

et al. 2015

OJCD

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Otosclerosis is an osteodystrophia of the otic capsule, responsible for hearing loss by blocking of the stapes footplate. The purpose of this study was to evaluate the reliability of computed tomography (CT) in the positive diagnosis of otosclerosis, to compare the radiological findings to those intraoperatively, and to seek a correlation between imaging data and postoperative audiometric results. This is a retrospective study of 60 patients having otosclerosis, treated in our department between 2009 and 2011. All patients underwent an otoscopic examination, pure tone and vocal audiometry, impedancemetry and petrous CT scan. At petrous CT scan, a footplate thickening was found in 9 cases. Labyrinthine bone hypodensity was noted in 51 cases. Sensitivity of CT in the diagnosis of otosclerosis was 100%. Regarding the operative findings and their correlation with imaging, we found that among the 7 facial canal procidences reported intraoperatively, CT had identified 6, with a sensitivity of 86%. Of the 53 facial nerve in normal position intraoperatively, CT had only identified 34, with a specificity of 64%. Regarding the ossicles, there were 6 cases of abnormalities of the incus, among them 3 were identified on CT, with a sensitivity of 50%. The 54 patients with normal ossicular chain intraoperatively were all identified as such on CT, with a specificity of 100% (p = 0.001). For correlation between imaging and postoperative results, it was found that patients with extended otosclerosis had lower postoperative audiometric improvement than those having localized disease (p < 0.05). Computed tomography is necessary for the diagnosis of otosclerosis. It also helps, with good sensitivity and specificity, seeking for anatomical variants that the surgeon could possibly encounter during surgical procedure. Finally, there is a statistically significant correlation between imaging data and postoperative audiometric results, allowing establishing a functional prognosis even before surgery.

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Otosclerosis

Abstract: CBCT is a new imaging technique with a considerably lower radiation dose than conventional MSCT. Our study indicates that CBCT is suitable and, in many ways, equivalent to MSCT, for temporal bone imaging in otosclerosis.

Cited by 33 publications

References 20 publications

Visualization of anatomical structures in the fetlock region of the horse using cone beam computed tomography in comparison with conventional multidetector computed tomography

Visualization of anatomical structures in the fetlock region of the horse using cone beam computed tomography in comparison with conventional multidetector computed tomography

Comparative study of the sensitivity of ultra-high-resolution CT and high-resolution CT in the diagnosis of isolated fenestral otosclerosis

Otosclerosis: Contribution of Computed Tomography and Radio-Anatomical Correlations

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