“…In Bi-based cuprates, the PG can also be manipulated by controlling an out-of-plane disorder, which is caused by a substitution at Sr in the Sr-O plane by other atoms [22,23]. For example, in Bi 2 Sr 2−x R x CuO 6+δ (R-Bi2201), by the substitution of Sr with lanthanides (R) from La to Eu, the Fermi arc shrinks and the PG energy and its spatial inhomogeneity increase, as observed by ARPES and STM/STS, respectively [24][25][26]. The correlation between spatial inhomogeneities and the PG has also been observed through STM/STS experiments in Bi2212, wherein the PG energy gap is spatially inhomogeneous, unlike the spatially uniform SC gap [7,27,28].…”