Outbreak of parvovirus B19 infection among anesthesiology and surgical fellows

Lara-Medrano, Reynaldo; Martínez‐Reséndez, Michel F.; Garza‐González, Elvira; Medina-Torres, Ana Gabriela; Camacho-Ortíz, Adrián

doi:10.1016/j.ajic.2015.12.004

Cited by 3 publications

(3 citation statements)

References 9 publications

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“…24,25 According to some studies, parvoviruses can cause nosocomial cross-infection directly through contact with respiratory droplets or contaminated surfaces, and the parvovirus attack rates among patients or HCWs might not be as low as once thought. 12,13,26 Therefore, strict implementation of isolation measures, personal protection, and environmental cleaning and disinfection is crucial. 27 In our study, among the four isolated patients with B19V confirmed with blood samples by the laboratory, only two tested positive for B19V through throat swab samples; meanwhile, the detection value of the remaining two patients did not reach the positive threshold.…”

Section: Discussionmentioning

confidence: 99%

“…However, to the best of our knowledge, this is the first study to examine the environmental hygienic monitoring of parvovirus B19 in a kidney transplantation ward of a general hospital, although there have been many reports of hospital outbreaks of B19V. 12,30,31 Our study provides an important evidence-based basis and reference value for providing targeted disinfection guidance and avoiding parvovirus cross-infection for immunosuppressed patients undergoing kidney transplantation.…”

Section: Dovepressmentioning

confidence: 96%

“…4 Due to the relative ease of spread of the virus among both hospital staff and patients, the risk of nosocomial spread of the disease, acquired from close contact or environmental surfaces, is quite high, with reported attack rates of 50%. 12,13 Control measures such as prompt disinfection, hand hygiene, ward closure, and B19V education are likely crucial for containing transmission. 14 To avoid the contagion, standard and droplet precautions and isolation should be implemented.…”

Section: Introductionmentioning

confidence: 99%

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Environmental Monitoring of Parvovirus B19 in the Kidney Transplantation Ward of a Chinese Teaching Hospital

Wang¹,

Zhan²,

Yu³

et al. 2022

IDR

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Parvovirus B19 (B19V) infection is a viral threat after kidney transplantation. It is mainly transmitted by close-contact inhalation of aerosolized viral particles. The risk of nosocomial spread of B19V in the transplantation ward is quite high. This study aimed to evaluate the quality of routine disinfection and the effectiveness of isolation measures in the wards of B19V-infected kidney transplant recipients. Patients and Methods: Throat swab samples of 19 kidney transplant recipients admitted to the isolation ward and three healthcare workers (HCWs) were collected for viral DNA detection. Routine disinfection procedures were performed twice a day in general and B19V isolation wards. Environmental surface and air samples were collected for viral DNA detection before and after disinfection. Results: A total of four patients were diagnosed with B19V infection and transferred to the B19V isolation ward, of which only two had positive throat swab samples. The other 15 patients and all HCWs tested negative for B19V. A total of 88 environmental surface and air samples were collected. Eight of the environmental samples collected in the B19V isolation ward before disinfection tested positive for B19V, while one sample tested positive after disinfection. In the general wards, all environmental samples collected before disinfection tested negative for B19V. All 24 samples collected from ambient air, whether in B19V isolation or general wards, before or after disinfection, tested negative for B19V. Conclusion: Existing methods of routine or terminal disinfection for air and object surfaces were effective in eliminating B19V from object surfaces and ambient air in the isolation and general wards. Material surfaces that are exposed to high frequency and easily contaminated by blood, body fluids, and indoor air were the focus of cleaning and disinfection. Nosocomial cross-infection of other immunocompromised patients and HCWs can be avoided if appropriate prevention and control measures are taken.

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Section: Discussionmentioning

confidence: 99%

Section: Dovepressmentioning

confidence: 96%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Environmental Monitoring of Parvovirus B19 in the Kidney Transplantation Ward of a Chinese Teaching Hospital

Wang¹,

Zhan²,

Yu³

et al. 2022

IDR

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Management guidelines for pregnant health care workers exposed to infectious dermatoses

Reddy

Kollhoff

Murase

et al. 2020

International Journal of Women's Dermatology

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2Exanthematous diseases are frequently of infectious origin, posing risks, especially for 3 pregnant healthcare workers (HCWs) who treat them. The shift from cell-mediated (Th1 4 cytokine profile) to humoral (Th2 cytokine profile) immunity during pregnancy can influence the 5 mother's susceptibility to infection and lead to complications for both mother and fetus. The 6 potential for vertical transmission must be considered when evaluating the risks for pregnant 7 HCWs treating infected patients, as fetal infection can often have devastating consequences. 8Given the high proportion of women of childbearing age among HCWs, the pregnancy-related 9 risks of infectious exposure are an important topic in both patient care and occupational health. 10 Contagious patients with cutaneous manifestations often present to dermatology or pediatric 11 clinics, where female providers are particularly prevalent, as a growing number of these 12 physicians are female. Unfortunately, the risks of infection for pregnant HCWs are not well 13 defined. To our knowledge, there is limited guidance on safe practices for pregnant HCWs who 14 encounter infectious dermatologic diseases. In this article, we review several infectious 15 exanthems, their transmissibility to pregnant women, the likelihood of vertical transmission, and 16 the potential consequences of infection for the mother and the fetus. Additionally, we discuss 17 recommendations with respect to avoidance, contact and respiratory precautions, and the need 18 Sungkate et al., 2017) have demonstrated risk of transmission of parvovirus infection to HCWs 62 following exposure to infected patients. One single-center study at Children's Hospital of 63 Philadelphia found elevated risk of infection between exposed and unexposed staff (Bell et al., 64 1998). However, a cohort study of 87 HCWs exposed to two patients with parvovirus B19-65 induced aplastic crisis found no significant increase in parvovirus B19-specific immunoglobulin 66 M (IgM) and immunoglobulin G (IgG) antibodies when compared with unexposed health care 67 workers in the same facility (Ray et al., 1997). 68While the risk of transmission to HCWs has not been definitively identified, preventing 69 the transmission of PVB19 infection is important as it can lead to adverse pregnancy outcomes. 70PVB19 infection carries a 9% excess risk of miscarriage within the first 20 weeks of gestation, 71 and 2.9% risk of fetal hydrops between weeks 9 and 20 (Miller et al., 1998). 72 Management Recommendations: 73 It is recommended that pregnant HCWs should not be part of the care team for patients 74 with suspected PVB19 infection if possible. If exposure is suspected, risk assessment should 75consider the presence of an ongoing outbreak, as well as the extent of contact that the HCW had 76 with exposed patients. Droplet precautions should be strictly followed when caring for patients 77 with PVB19. Please refer to Table 1 for the different types of infection control and prevention 78 precautions. If a pregnant HCW is exposed to a kn...

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Human parvovirus B19 nosocomial outbreak in healthcare personnel in a paediatric ward at a national tertiary referral centre in Thailand

Sungkate

Phongsamart

Rungmaitree

et al. 2017

Journal of Hospital Infection

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Outbreak of parvovirus B19 infection among anesthesiology and surgical fellows

Cited by 3 publications

References 9 publications

Environmental Monitoring of Parvovirus B19 in the Kidney Transplantation Ward of a Chinese Teaching Hospital

Environmental Monitoring of Parvovirus B19 in the Kidney Transplantation Ward of a Chinese Teaching Hospital

Management guidelines for pregnant health care workers exposed to infectious dermatoses

Human parvovirus B19 nosocomial outbreak in healthcare personnel in a paediatric ward at a national tertiary referral centre in Thailand

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