Outbreak of tuberculosis after minimal exposure to infection.

Rao, Vinod; Joanes, R.F.; Kilbane, Paula; Galbraith, N. S.

doi:10.1136/bmj.281.6234.187

Cited by 31 publications

(8 citation statements)

References 2 publications

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“…4 The outbreak reported here occurred in an area of low prevalence but after prolonged and close contact with an infectious patient. This patient's symptoms were minimal and had developed in the previous th-ee months.…”

Section: Discussionmentioning

confidence: 85%

Tuberculosis in a primary school: the Uppingham outbreak.

Wales¹,

Buchan²,

Cookson³

et al. 1985

BMJ

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Section: Discussionmentioning

confidence: 85%

Tuberculosis in a primary school: the Uppingham outbreak.

Wales¹,

Buchan²,

Cookson³

et al. 1985

BMJ

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“…Although airborne transmission of pulmonary tuberculosis does still occur (Rao et al 1980) it is antibacterial treatment which controls its spread, not only by treating the disease but also by the rapid elimination of bacterial dispersal by the patient.…”

Section: Resultsmentioning

confidence: 99%

Joseph Lister and Infection from the Air

Lidwell¹

1987

Epidemiol. Infect.

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In his book, Floating Matter of the Air, John Tyndall (Tyndall, p. 262) quotes from Robert Boyle's ‘Essay on the Pathological Part of Physik’ ‘that he who thoroughly understands the nature of ferments and fermentations shall probably … give a fair account of divers phenomena of several diseases, which will perhaps be never properly understood without an insight into the doctrine of fermentations'. It was more than a century and a half before the first part of this suggestion was fulfilled, after which the unravelling of the causes of infective diseases proceeded rapidly. In 1836 de la Tour and, almost simultaneously, Schwann (Tyndall, p. 7) discovered, in yeast, the agent of fermentation as a living organism which reproduced itself in endless succession. Schwann also observed that putrefaction in meat broth did not set in if this was kept in contact, not with ordinary air, but with air which had been previously brought to a high temperature.

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“…The environment and the clinical characteristics of each case were considered as the most important factors in the transmission variability 14–18 . Several possible explanations could be given to justify the difference in infectivity in these two index cases.…”

Section: Discussionmentioning

confidence: 99%