Outcome at Six Months After Primary Percutaneous Coronary Interventions Performed at a Rural Satellite Center of Sindh Province of Pakistan

Mujtaba, Syed Fayaz; Khan, M. Gabriel; Sohail, Hina; Sial, Jawaid Akbar; Karim, Musa; Saghir, Tahir; Abbas, Kiran; Ahmed, Moiz; Qamar, Nadeem

doi:10.7759/cureus.8345

Cited by 3 publications

(3 citation statements)

References 32 publications

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“…About 34.6% of the patients have single-vessel disease. Similar results have been reported by Mujtaba et al in their study conducted in Sindh, Pakistan [13].…”

Section: Discussionsupporting

confidence: 91%

Experience and Outcomes of Primary Percutaneous Coronary Intervention in a Tertiary Care Hospital in South Punjab, Pakistan

Akhtar,

Saleemi,

Zarlish

et al. 2023

Cureus

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Background: Primary percutaneous coronary intervention (PCI) is the emergency procedure and gold standard for the treatment of ST-Elevation Myocardial Infarction (STEMI).Objective: To share the experience and outcomes of primary PCI in a tertiary care hospital in South Punjab, Pakistan.Methods: A descriptive cross-sectional study was planned from the 1 st of April, 2023 to the 30 th of September, 2023. All patients presenting with acute STEMI undergoing primary PCI were included in the study. Data regarding patient demographics, risk factors, procedural characteristics, time variables, and inhospital events was observed.Results: A total of 1132 patients were included in the study. There were 934 (82.5%) males. Smoking is the most common risk factor among all the patients. Anterior wall myocardial infarction is the most common STEMI and the left anterior descending artery is the culprit vessel in 58.3% (n=660) of patients. Single vessel disease was present in 34.6% (n=392) of the patients. Thrombolysis in Myocardial Infarction (TIMI )Flow III was achieved in 80% (n=906) of patients after primary PCI. The average total ischemic time of the patients included in the study was 5 hours and 48 minutes, with a standard deviation of 3 hours and 55 minutes. Our mortality was 3.5% (n=40). Conclusion: Our patients take a longer time to present to the PCI-capable centers. Despite their late presentation, primary PCI has better outcomes for treating acute STEMI.

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“…About 34.6% of the patients have single-vessel disease. Similar results have been reported by Mujtaba et al in their study conducted in Sindh, Pakistan [13].…”

Section: Discussionsupporting

confidence: 91%

Experience and Outcomes of Primary Percutaneous Coronary Intervention in a Tertiary Care Hospital in South Punjab, Pakistan

Akhtar,

Saleemi,

Zarlish

et al. 2023

Cureus

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“…Niccoli et al . [ 10 ] and other clinical trials[ 11 12 13 14 ] assesses the importance of micro vasculature on myocardial function recovery in patients with acute myocardial function showed the myocardial remodeling and stunning are the predictors of prognosis.…”

Section: Discussionmentioning

confidence: 99%

Left Ventricular Functional Remodeling after Primary Percutaneous Coronary Intervention

Batra

Malik²,

Khan

et al. 2022

Journal of Cardiovascular Echography

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Background: Improvement in left ventricular (LV) function after revascularization is an important determinant of long-term prognosis in a patient with acute myocardial infarction (AMI). However, data on the changes of LV function after revascularization are scarce in our population. Hence, this study was conducted to evaluate the changes in LV function and dimensions by echocardiography at 3 and 6 months after primary percutaneous coronary intervention (PCI). Materials and Methods: A total of 188 patients were recruited in this study who had undergone primary PCI. Patients with preexistent LV dysfunction, prior PCI, or with congenital heart disease were excluded. Echocardiography was performed at baseline (within 24 h of intervention), 3 months, and 6 months of intervention. Remodeling in terms of change in LV ejection fraction (LVEF), LV end-diastolic dimension (LVEDD), LV end-systolic dimension, and wall motion score index (WMSI) was evaluated. Results: Out of the 188 patients, 90.4% were male, and mean age was 53.94 ± 9.12 years. Baseline mean LVEF was 39.79 ± 6.2% with mean improvement of 5.11 ± 3.87 (P < 0.001) at 3 months and 6.38 ± 4.29 (P < 0.001) at 6 months. Baseline LVEDD was 46.23 ± 3.86 mm which improved to 44.68 ± 2.81 mm at 6 months. Basal WMSI decreased by -0.09 ± 0.08 and -0.13 ± 0.09 at 3 and 6 months, respectively, after revascularization. Conclusions: Primary PCI is the recommended mode of reperfusion in patients with AMI. It reduces infarct size, maintains microvascular integrity and preserves LV systolic function hence improving LV function.

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“…The current standard protocols for the management of AMI involve the frequent use of percutaneous coronary intervention (PCI; Angioplasty with stenting) to restore perfusion. PCI has demonstrated a tremendous reduction in mortality and has allowed for early discharges [ 3 ]. Furthermore, it also improved the quality of life in patients with myocardial infarction [ 4 ].…”

Section: Introductionmentioning

confidence: 99%

Effectiveness of Cardiac Rehabilitation in Myocardial Infarction Patients After Percutaneous Coronary Intervention

Shah¹,

Jamal²,

Ullah³

et al. 2022

Cureus

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Outcome at Six Months After Primary Percutaneous Coronary Interventions Performed at a Rural Satellite Center of Sindh Province of Pakistan

Cited by 3 publications

References 32 publications

Experience and Outcomes of Primary Percutaneous Coronary Intervention in a Tertiary Care Hospital in South Punjab, Pakistan

Experience and Outcomes of Primary Percutaneous Coronary Intervention in a Tertiary Care Hospital in South Punjab, Pakistan

Left Ventricular Functional Remodeling after Primary Percutaneous Coronary Intervention

Effectiveness of Cardiac Rehabilitation in Myocardial Infarction Patients After Percutaneous Coronary Intervention

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