Outcome of conventional IVF and ICSI on sibling oocytes in mild male factor infertility

Plachot, M.

doi:10.1093/humrep/17.2.362

Cited by 108 publications

(86 citation statements)

References 33 publications

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“…This result is due to ensured sperm entry into the oocyte, thereby bypassing the zona pellucida and acrosome reaction necessary for in vivo fertilization or CI [4,16,31]. On the other hand, others have theorized that using ICSI may bypass natural selection methods and choose abnormal sperm, resulting in poor outcomes.…”

Section: Discussionmentioning

confidence: 99%

Should ICSI be recommended routinely in patients with four or fewer oocytes retrieved?

Luna

Bigelow

Duke

et al. 2011

J Assist Reprod Genet

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Purpose To determine if patients with a low response to controlled ovarian hyperstimulation during IVF benefit from intracytoplasmic sperm injection (ICSI) Methods Retrospective analysis of 350 IVF cycles in which four or fewer oocytes were retrieved. Severe male factor cases were excluded from analysis. Conventional insemination (CI) and ICSI were compared, with primary outcome measures of fertilization rate, implantation rate, clinical pregnancy rate per embryo transfer, and pregnancy loss rate. Result(s) Fertilization rates per oocyte retrieved for CI and ICSI were comparable (51.5% vs. 51.8%). Parallel implantation rates (22% vs. 25%), clinical pregnancy rates (32.8% vs. 33.3%), and loss rates (26.7% vs. 39.5%) were also noted. No difference in cancelled cycles was reported. Conclusion(s) Our results demonstrate that in the presence of normal semen parameters, low egg number is not an indication to perform ICSI.

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Section: Discussionmentioning

confidence: 99%

Should ICSI be recommended routinely in patients with four or fewer oocytes retrieved?

Luna

Bigelow

Duke

et al. 2011

J Assist Reprod Genet

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show abstract

“…Generally, the levels of FSH correlate with the number of spermatogonia: when spermatogonia are absent or markedly diminished, FSH values are usually elevated; when the number of spermatogonia is normal, but maturation arrest exists at the spermatocyte or spermatid level, FSH values are within the normal range. However, for an individual patient, FSH levels do not accurately predict the spermatogenesis status because men with maturation arrest histology could have normal FSH and normal testis volume and still be azoospermic [12,132]. Testicular biopsy can be part of intracytoplasmic sperm injection (ICSI) treatment in patients with clinical evidence of NOA.…”

Section: Diagnosis and Management For Infertilitymentioning

confidence: 99%

Male Infertility; Evidences, Risk Factors, Causes, Diagnosis and Management in Human

Sharma¹

2017

Ann Clin Lab Res

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Infertility has become ominous problem. On an average, about 10% of all couples face difficulty in starting a family and this creates a feeling of great personal failure, particularly in India where religious and socio-economic traditions have made it almost imperative for everyone to have children. A significant association had been found between impaired semen quality including sperm count, motility and morphology. In this review, the various contributory etiological factors i.e., exposure to heavy metals, pesticides, industrial chemicals, endocrine factors, genetics causes and modern life style had been discussed which have a serious impact on male infertility. In this article we analyzed data from different sources and present evidences of the possible etiology and risk factors for male infertility. There is a need to emerge at the indiscriminate use and disposal of environmental chemicals. Especially pesticides and industrial chemicals as the chemicals enter the food chain, surface and ground water which had potential for exposure during the critical period of development further avoiding tobacco smoking, excessive alcoholism, excessive heat exposure to the testes can help in improving the semen quality.

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“…34 Occasionally, a combination of morphology and motile count is analyzed. Plachot et al 35 propose that at least 0.5 million normal, progressively motile sperm per milliliter must be present in the ejaculate in order to recommend conventional IVF. Contemporary strategies for deciding between IVF and ICSI are either formulated using these experience-based, preset cutoff values or created with the assumption that ICSI is the more robust insemination technique.…”

Section: Ivf or Icsi For Male Factor Infertilitymentioning

confidence: 99%

Male factor infertility and ART

Tournaye¹

2011

Asian J Androl

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Outcome of conventional IVF and ICSI on sibling oocytes in mild male factor infertility

Abstract: This strategy enabled us to avoid 32.8% of complete fertilization failures after IVF, but not to decrease significantly the number of ICSI attempts in subsequent cycles. However, the uncertainties concerning the safety of ICSI suggest that ICSI should be used cautiously and judiciously.

Cited by 108 publications

References 33 publications

Should ICSI be recommended routinely in patients with four or fewer oocytes retrieved?

Should ICSI be recommended routinely in patients with four or fewer oocytes retrieved?

Male Infertility; Evidences, Risk Factors, Causes, Diagnosis and Management in Human

Male factor infertility and ART

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