2014
DOI: 10.14260/jemds/2014/2471
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Outcome of Neonates With Thrombocytopenia

Abstract: To determine etiology, onset, clinical features and outcome of neonates with thrombocytopenia. METHODS: 140 neonates having bleeding or having platelet count (<1.5lakhs/µl) were selected from those admitted to NICU'S attached to MR Medical College, Gulbarga. Initial platelet count was done on admission and counts were repeated 12 hours after any therapeutic intervention. OBSERVATION AND RESULTS: Severe thrombocytopenia (<50000/µl) was present in 8.5%, moderate (50, 000-1, 00, 000/µl) in 17%. Majority (45.33%) … Show more

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Cited by 5 publications
(11 citation statements)
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“…The prevalence of moderate and severe thrombocytopenia in present study was comparable with the study done by S. Patil et al, and Rameshbabu et al 5,10 In a study done by Anubha Sharma et al, and Keerthi Tirupathi et al, study and Lea bonifacio et al, study there was more number of babies with thrombocytopenia in moderate and severe group. 8,9,11 The higher prevalence of severe thrombocytopenia is probably due to higher proportion of septicemic neonates in NICU admissions.…”
Section: Totalsupporting
confidence: 90%
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“…The prevalence of moderate and severe thrombocytopenia in present study was comparable with the study done by S. Patil et al, and Rameshbabu et al 5,10 In a study done by Anubha Sharma et al, and Keerthi Tirupathi et al, study and Lea bonifacio et al, study there was more number of babies with thrombocytopenia in moderate and severe group. 8,9,11 The higher prevalence of severe thrombocytopenia is probably due to higher proportion of septicemic neonates in NICU admissions.…”
Section: Totalsupporting
confidence: 90%
“…This is comparable with Patil et al, study (63.5% and 36.5% respectively) and Natani BS et al, study (62.5% and 37.5% respectively). 5 In the present study, Septicemia was seen in 58.3% cases. Septicemia was strongly associated with thrombocytopenia, especially the severe variety (p=0.008).…”
Section: Totalsupporting
confidence: 54%
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“…27 (13.5%) babies had PIH as the maternal risk factor and it was associated with severe thrombocytopenia.In studies conducted by khalessi et al and patil et al, the percentage of babies with PIH as maternal risk factor was 17.7% and 72.17%. 7,16 The thrombocytopenia associated with PIH is almost always mild to moderate and caused by decreased platelet production as the main mechanism and decreased concentrations of circulating megakaryocyte progenitors. In this study, PIH was associated with severe thrombocytopenia.…”
Section: Maternal Risk Factorsmentioning
confidence: 99%
“…4,3,7 In studies conducted by Patil et al, Basil and Zaccheaus et al, sepsis was associated with severe thrombocytopenia which was similar to the results in our study. 10,16,21 Septicemia leads to thrombocytopenia due to both decreased production and increased consumption of platelets and hence results usually in severe thrombocytopenia.…”
Section: Neonatal Factorsmentioning
confidence: 99%