To determine etiology, onset, clinical features and outcome of neonates with thrombocytopenia. METHODS: 140 neonates having bleeding or having platelet count (<1.5lakhs/µl) were selected from those admitted to NICU'S attached to MR Medical College, Gulbarga. Initial platelet count was done on admission and counts were repeated 12 hours after any therapeutic intervention. OBSERVATION AND RESULTS: Severe thrombocytopenia (<50000/µl) was present in 8.5%, moderate (50, 000-1, 00, 000/µl) in 17%. Majority (45.33%) were preterm and the major cause was sepsis in 51.3%.Mucosal bleed was the most common presentation. Mortality was 37% in severe and 3.9% in moderate thrombocytopenia group. CONCLUSION: Significant association is observed with maternal PIH, Late onset sepsis, NEC and sepsis with DIC .Prematurity, IUGR, Birth asphyxia were common associated morbidities. Severe thrombocytopenia in sick neonates, in NICU, is a poor prognostic indicator.

Background: Acute intestinal obstruction is one of common abdominal emergency and is associated with significant morbidity and mortality especially if it progresses to bowel ischemia. The diagnosis and management of the patient with intestinal obstruction is one of the more challenging emergencies that a general surgeon can come across. Although the mortality due to acute intestinal obstruction is decreasing with better understanding of pathophysiology and improvement in diagnostic techniques, fluid and electrolyte correction, much potent anti-microbials but still mortality ranges from 10-15% and more so in developing countries.Methods: The study will be conducted in the department of general surgery with symptoms and signs of acute intestinal obstruction admitted in the surgical ward. Fifty cases of intestinal obstruction have been studied. Patients belonged to all the age groups except infants are included in present study. The criteria for selection of cases was based on clinical history, physical findings, radiological and haematological investigations. The study was divided into clinical study, investigations and treatment. The results are tabulated stressing on following points age, sex, symptoms examination findings, investigations, abnormalities, probable causative factors, operative findings and operative procedure adopted and complications if any.Results: The commonest cause of intestinal obstruction in the adults in this study series was postoperative adhesions (36%) followed by obstructed/strangulated hernia (26%). Malignancy of the large bowel was seen in 9 cases constituting 18% of cases where as incidence of Volvulus of bowel was 4% in this series. Although pulmonary tuberculosis is more prevalent in India due to advent in use of antitubercular drugs incidence of abdominal tuberculosis is becoming less. In present study incidence of ileocaecal tuberculosis was 10%. One case of mesenteric ischaemia was present in our study.Conclusions: Acute intestinal obstruction remains an important surgical emergency in the surgical field. Success in the treatment of acute intestinal obstruction depends largely upon its early diagnosis, skilful management and treating the pathological effects of the obstruction just as much as the cause itself.

Background: Emergency Obstetric Hysterectomy (EOH) is removal of uterus following vaginal delivery, Emergency LSCS or within the puerperium period. Because of increasing caesarean deliveries, the number of scarred uterus is increasing exposing the gravid women to increasing morbidity from uterine rupture, placenta accrete and placenta previa thus increasing the incidence of Emergency obstetric hysterectomy. The aim was to determine the incidence, demographic details, high risk factors and fetomaternal outcome of patients who underwent EOH.Methods: This was a retrospective study where data was collected from the record sheets of patients who underwent Emergency Obstetric Hysterectomy from January 2016 to December 2017 in the department of OBG, GIMS Gulbarga. Maternal age, parity, socioeconomic status, antenatal care, high risk factors and fetomaternal outcome were analysed.Results: During the study period there were 17,820 deliveries out of which 20 cases underwent EOH giving an incidence of 0.12%. Most of patients were uneducated, unbooked, low SES and of rural background and were multiparous. Main cause for EOH were rupture uterus, PPH and morbidly adherent placenta. There were 2 cases of maternal mortality and fetal mortality was 65%.Conclusions: Though EOH is a lifesaving procedure it curtails the reproductive capacity of the women. Proper antenatal care, early referral, timely decision and skill of surgeon in performing this procedure is important.