Outcome of surgical complications following simultaneous pancreas-kidney transplantation

Banga, Neal; Hadjianastassiou, Vassilis G.; Mamode, Nizam; Calder, Francis; Olsburgh, Jonathon; Drage, Martin; Sammartino, Cinzia; Koffman, Geoff; Taylor, John

doi:10.1093/ndt/gfr502

Cited by 49 publications

(62 citation statements)

References 36 publications

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“…Previous studies have shown that SPKT recipients with early technical failure of the pancreas have significantly inferior kidney graft survival rates compared to those who did not (59.5% vs 82% at three years, P < .001) [7]. Contrary to this, Banga [8] reveals that longterm kidney survival remains unaffected in patients who experience early re-laparotomy compared to those who did not (82% versus 83%, at 5 years P ¼ .412). In our study, the survival rate of kidney grafts was lower among patients who presented with grades IIIb or IVa-b complications than those who did not have early technical failure (kidney survival rate at 5 years 81.8% vs 97.3%; P ¼ .02), showing an independent influence adjusted for immunologic and other important variables that influence postoperative complications.…”

Section: Discussionmentioning

confidence: 91%

“…Most published articles focus on complications that require reoperation but do not use available reporting systems [8,13,14], which will allow series comparison and conclusions to be reached to avoid complications and improve patient care. To address this need, there has been an increase in the number of studies using the ClavienDindo system [15e17].…”

Section: Discussionmentioning

confidence: 99%

“…Several investigators have described the negative influence with postoperative complications in SPKT forecast, although most of them focus on pancreas graft prognosis, with which the majority of complications are associated [6]. There is little and controversial literature about the influence of these complications in graft kidney medium and long-term prognosis [7,8].…”

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confidence: 99%

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Influence of Surgical Complications on Kidney Graft Survival in Recipients of Simultaneous Pancreas Kidney Transplantation

Campos-Hernández

Gómez

Carrasco‐Valiente

et al. 2015

Transplantation Proceedings

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Section: Discussionmentioning

confidence: 91%

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

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Influence of Surgical Complications on Kidney Graft Survival in Recipients of Simultaneous Pancreas Kidney Transplantation

Campos-Hernández

Gómez

Carrasco‐Valiente

et al. 2015

Transplantation Proceedings

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“…This suggests that surgical complications are associated with strong non-immunologic complications after transplantation in the early postoperative period [10]. Anticoagulation therapy after SPK transplantation is also involved.…”

Section: Discussionmentioning

confidence: 99%

Outcomes following Simultaneous Pancreas-Kidney Transplantation: Single Center Experience in Korea

Lee¹,

Kim²,

Cho³

et al. 2017

Trends in Transplant

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Purpose: Among organ transplantation, simultaneous pancreas-kidney (SPK) transplantation is becoming increasingly common in patients with type I and II diabetes mellitus (DM). The purpose of this study is to review SPK transplantation cases and learn the lessons from the experience performed at out institution. Methods:We retrospectively reviewed and the analyzed the medical records of 25 SPK transplantation recipients performed from January 2003 to June 2016 in Korea.Results: 25 cases of SPK transplantation were type I DM patients. Twenty-four patients (seven males and 18 females) underwent SPK transplantation from deceased donors, and one female patient received living kidney transplantation. Enteric exocrine drainage via pancreas graft drainage was done in all cases. There were 10 acute rejection cases; all were relieved by steroid pulse therapy. Kidney graft loss occurred in four patients and two pancreatectomy graft surgeries were performed due to one graft necrosis and the other graft rejection. Insulin injection or oral hypoglycemic agents were used for three patients. With the exception of five mortality cases, 20 patients stopped insulin and oral hypoglycemic agents after transplantation. Blood glucose level was maintained within normal range without medication in 16 patients.Conclusion: SPK transplantation is a multiple organ transplantation that requires careful treatment to avoid complications in the postoperative period. SPK transplantation can render insulin dependent type I DM patients with end stage renal disease (ESRD) free from insulin use and produce proper graft functions.

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“…Refinements in surgical technique and immunosuppressive therapy have considerably improved outcome; however, the complication rate remains still at about 25% [47].…”

Section: Pancreas Transplantationmentioning

confidence: 99%

Robot-Assisted Transplant Surgery - Vision or Reality A Comprehensive Review

Stiegler¹,

Schemmer²

2018

Visc Med

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Minimally invasive surgery is standard procedure for many operations. Further refinements include the introduction of robotic surgery which is still an emerging field especially in laparoscopic surgery. Since the successful introduction of the da Vinci Robotic Surgical System, the robotic approach in organ transplantation has become of great interest in both the live donor organ retrieval and the recipient operation. Robotic surgery for kidney, liver, and pancreas transplantation is feasible. Over 700 donor nephrectomies and 100 kidney transplantations have been performed already, and robotic surgery is standard in a small number of pioneer centers; however, larger series and most importantly randomized controlled trials for the highest evidence are needed. Longer warm ischemia time and higher costs limit these procedures at the moment.

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Outcome of surgical complications following simultaneous pancreas-kidney transplantation

Abstract: Surgical complications following SPK transplantation can cause significant morbidity and adversely affect pancreas graft survival, but do not affect long-term kidney or patient survival.

Cited by 49 publications

References 36 publications

Influence of Surgical Complications on Kidney Graft Survival in Recipients of Simultaneous Pancreas Kidney Transplantation

Influence of Surgical Complications on Kidney Graft Survival in Recipients of Simultaneous Pancreas Kidney Transplantation

Outcomes following Simultaneous Pancreas-Kidney Transplantation: Single Center Experience in Korea

Robot-Assisted Transplant Surgery - Vision or Reality A Comprehensive Review

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