Outcome of surgical fundoplication for extra-oesophageal symptoms of reflux

Iqbal, Mohd; Batch, A. J. G.; Moorthy, Krishna; Cooper, Barrett R.; Spychal, Robert

doi:10.1007/s00464-008-9861-8

Cited by 27 publications

(23 citation statements)

References 13 publications

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“…These results are consistent with prior studies, which demonstrated postoperative resolution or improvement of typical symptoms [8,15,[18][19][20]. Study results showed excellent symptom resolution following both primary and reoperative paraesophageal herniorrhaphy, as evidenced by significant reductions in all composite and individual esophageal and extraesophageal symptom scores in the follow-up period when compared with preoperative scores.…”

Section: Discussionsupporting

confidence: 92%

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Reoperative laparoscopic paraesophageal herniorrhaphy can produce excellent outcomes

et al. 2010

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Section: Discussionsupporting

confidence: 92%

“…Reoperative paraesophageal herniorrhaphy patients in this study showed near-complete resolution of their esophageal and extraesophageal symptoms, similar to other studies [14,17,19]. These findings somewhat contradict the findings of Khaitan et al in terms of satisfaction rates following primary or reoperative procedures.…”

Section: Discussioncontrasting

confidence: 57%

Reoperative laparoscopic paraesophageal herniorrhaphy can produce excellent outcomes

et al. 2010

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“…The symptomatic outcome of patients in this study supports the more promising results of other studies on patients with extraesophageal symptoms as the main indication for LNF [16,18,27,28,29]. The symptomatic outcome of LNF for LPR in our study is similar to LNF results for typical GERD symptoms, also at long-term follow-up [9,17].…”

Section: Discussionsupporting

confidence: 81%

Long-Term Outcomes after Laparoscopic Nissen Fundoplication for Reflux Laryngitis

Karvonen

Ovaska

2010

Dig Surg

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Background: The surgical treatment of gastroesophageal reflux-induced reflux laryngitis remains controversial. The aim of this study was to determine both long-term objective endoscopic findings and subjective symptomatic outcomes after laparoscopic Nissen fundoplication in patients operated on for reflux laryngitis. Methods: 40 consecutive patients with pH-proven reflux laryngitis underwent laparoscopic Nissen fundoplication between 1998 and 2002. 68% (n = 27) of these patients underwent an endoscopic evaluation and 90% (n = 36) were available for the subjective long-term outcome (personal interviews). Results: At a median follow-up of 91 months there were no disrupted plications, none of the patients had esophagitis but 3 recurrent hiatal hernias were detected. 61% of the patients reported no or only mild reflux laryngitis symptoms postoperatively and 69% of the patients evaluated their voice quality improved after surgery. 94% of the patients were satisfied with their surgical result. With benefit of hindsight, 11% of the patients would not choose surgical treatment and 42% had reinitiated antireflux medications postoperatively. Conclusion: The majority of pH-proven gastroesophageal reflux-induced reflux laryngitis patients attain long-term symptomatic benefit and satisfaction on the surgical outcome, and with proper patient selection laparoscopic Nissen fundoplication provides a feasible long-term treatment option for reflux laryngitis.

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“…The GIQLI questionnaire has been recommended by the European Association for Endoscopic Surgery for the assessment of quality of life after fundoplication [26]. The DeMeester reflux questionnaire is validated to assess reflux symptoms and the RSI has been validated in nontransplant patients as a marker of extra-oesophageal reflux [13], and has been used to assess the effects of fundoplication on extraoesophageal reflux [27,28].…”

Section: Discussionmentioning

confidence: 99%

Anti-reflux surgery in lung transplant recipients: outcomes and effects on quality of life

Robertson¹,

Krishnan²,

Ward³

et al. 2011

Eur Respir J

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Fundoplication may improve survival after lung transplantation. Little is known about the effects of fundoplication on quality of life in these patients. The aim of this study was to assess the safety of fundoplication in lung transplant recipients and its effects on quality of life.Between June 1, 2008 and December 31, 2010, a prospective study of lung transplant recipients undergoing fundoplication was undertaken. Quality of life was assessed before and after surgery. Body mass index (BMI) and pulmonary function were followed up.16 patients, mean¡SD age 38¡11.9 yrs, underwent laparoscopic Nissen fundoplication. There was no peri-operative mortality or major complications. Mean¡SD hospital stay was 2.6¡0.9 days. 15 out of 16 patients were satisfied with the results of surgery post fundoplication. There was a significant improvement in reflux symptom index and DeMeester questionnaires and gastrointestinal quality of life index scores at 6 months. Mean BMI decreased significantly after fundoplication (p50.01). Patients operated on for deteriorating lung function had a statistically significant decrease in the rate of lung function decline after fundoplication (p50.008).Laparoscopic fundoplication is safe in selected lung transplant recipients. Patient benefit is suggested by improved symptoms and satisfaction. This procedure is acceptable, improves quality of life and may reduce deterioration of lung function.

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Outcome of surgical fundoplication for extra-oesophageal symptoms of reflux

Abstract: Surgery can be an effective treatment in the majority of patients with extra-oesophageal symptoms of reflux.

Cited by 27 publications

References 13 publications

Reoperative laparoscopic paraesophageal herniorrhaphy can produce excellent outcomes

Reoperative laparoscopic paraesophageal herniorrhaphy can produce excellent outcomes

Long-Term Outcomes after Laparoscopic Nissen Fundoplication for Reflux Laryngitis

Anti-reflux surgery in lung transplant recipients: outcomes and effects on quality of life

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