Outcome of surgical release among diabetics with carpal tunnel syndrome11No commercial party having a direct financial interest in the results of the research supporting this article has or will confer a benefit upon the authors(s) or upon any organization with which the author(s) is/are associated.

Minimal Clinically Important Difference of Carpal Tunnel Release in Diabetic and Nondiabetic Patients

“…10 Mondelli and others also achieved a similar result by reporting significant improvement and satisfaction after the carpal tunnel release in diabetic patients. 6–8,28,29 Because of a lack of high-grade evidence, both the American Academy of Orthopaedic Surgery and the American Academy of Neurology do not make any specific recommendations with regards to the surgical treatment (one way or another) of carpal tunnel syndrome on diabetic patients. 9,30 …”

“…3–5 Despite its high prevalence in the diabetic population, studies reporting outcomes of surgical treatment in this patient group are limited. 6–10 Outcomes based on recovery of muscle wasting and sensory loss did not appear to be favorable for diabetic patients. 6 However, these physical examination findings may not reflect patients’ self-reported outcomes such as satisfaction.…”

“…6–10 Outcomes based on recovery of muscle wasting and sensory loss did not appear to be favorable for diabetic patients. 6 However, these physical examination findings may not reflect patients’ self-reported outcomes such as satisfaction. Patient-reported outcome measures are necessary in the evaluation of surgical interventions to appropriately reflect patient’s opinion and overall satisfaction.…”

Effects of decompression on behavioral, electrophysiologic, and histomorphologic recovery in a chronic sciatic nerve compression model of streptozotocin-induced diabetic rats

“…Some clinical and electrophysiologic results have showed less than favorable results 13,14,38,39. However, others have found some beneficial outcomes 10,11,40. In our study, thermal hyperalgesia recovery after decompression surgery occurred in both the nondiabetic and diabetic groups.…”

“…The results of carpal tunnel decompression in diabetic patients are controversial. Some studies have shown the results of surgery to be similar in both diabetic and normal patients 10–12. Others have shown a less favorable response in diabetic patients 13,14…”