Outcomes of emergent embolisation of ruptured hepatocellular carcinoma in a western population

Management, outcomes, and prognostic factors of ruptured hepatocellular carcinoma: A systematic review

“…A large portion of the cohort population consisted of patients from Asia, as 22 studies (33%) were from China, 17 (25%) from Japan, 10 (15%) from Taiwan, 5 (7.5%) from Korea, 2 (3%) from Thailand, and 1 (1.5%) each from Singapore and Malaysia . In contrast, studies about rHCC were less common from Western centers with only 2 reports (3%) from the Netherlands and Italy, and 1 (1.5%) each from Canada, France, United Kingdom, USA, and Nigeria . The proportion of HCC patients who had rHCC varied across different studies and countries with a range from 1.6% to 26%.…”

“…Searching the reference list (snowball procedure) retrieved two additional articles. In total, 67 studies were deemed eligible and therefore included in the systematic review …”

“…Thirty‐five studies provided data on short‐term survival (Table ) . The leading causes of death in the short‐term was demise either from bleeding complications (34.3%) or hepatic failure (30.0%).…”

“…The long‐term outcomes among all patients in the cohort were summarized (Figure ) . Long‐term cause of death was related to cancer recurrence and metastasis (17.2% of overall cohort).…”

“…Forty‐one studies provided data on prognostic factors associated with OS (Table ) . While several studies noted that patients with rHCC had a worse long‐term prognosis, other reports failed to find an association between rHCC and long‐term survival .…”