Outdoor exposure in children from Buenos Aires Province, Argentina

Irigaray, L.; Balsa, Alejandro; Armesto, Alejandra; Magnetto, I.; Szeps, Abel; Iribarren, Luciano; Iribarren, Rafael; Grzybowski, Andrzej

doi:10.1016/j.oftale.2021.02.010

Cited by 1 publication

(1 citation statement)

References 22 publications

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“…[16][17][18] The method most frequently used by epidemiological studies to determine an individual's time spent outdoors has been questionnaires. 19,20 However, this data may not be accurate due to recall bias, inaccuracy of questions or errors of interpretation, 21,22 leading to overestimation or underestimation of the actual time spent outdoors. Therefore, more objective methods have been recently investigated to ensure valid results to implement preventive interventions.…”

Section: Introductionmentioning

confidence: 99%

Conjunctival Ultraviolet Autofluorescence as a Biomarker of Outdoor Exposure in Myopia: A Systematic Review and Meta-analysis.

Rodríguez,

Claici,

Castañeda

et al. 2023

Preprint

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Outdoor activity (OA) is considered the main modifiable risk factor for myopia development. Quantifying the association between Conjunctival Ultraviolet Autofluorescence (CUVAF) area and OA can be useful as a biomarker for myopia control. The purpose of this study is to quantify the association between CUVAF area and myopia. The articles included populations from different geographic areas (Europe/Asia/Australia) and ages. The bibliographic research was accomplished between June-August of 2022 with the following databases: MEDLINE/SCIENCE DIRECT/GOOGLE SCHOLAR/WEB OF SCIENCE/SCOPUS with all the terms related of "conjunctival ultraviolet autofluorescence” (2006-2022). Cross-sectional and case-control studies were included. The differences between CUVAF area and the hours of OA performed by myopic and non-myopic patients and the correlation of OA with the size of the CUVAF area were analyzed. The meta-analysis of the CUVAF area between myopic and non-myopic patients showed statistically smaller areas (-3.30 mm²-CI95%[-5.5;-1.06]). Stratified sub-analysis by different geographic areas showed that Australia-Asia patients showed a greater difference in CUVAF area (-4.92 mm²-CI95%[-9.5;-0.29]) compared to Europe patients (-1.97 mm²;CI95%;-2.8;-1.14, p= 0.007). Myopic reported less OA vs non-myopic (-3.38 hours/week-CI95%[-4.6;-2.09]), and the correlation between CUVAF area and OA was 0.14 (CI95%[0.09;0.19]). A strong relationship was observed between CUVAF, myopia and OA in different studies and geographic locations. The importance of this validation is that CUVAF is a simple, fast and non-invasive quantitative method to evaluate the control of myopia.

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