Outpatient Treatment of Acute Diverticulitis: Rates and Predictors of Failure

Etzioni, David A.; Chiu, Vicki; Cannom, Rebecca R.; Burchette, Raoul J.; Haigh, Philip I.; Abbas, Maher A.

doi:10.1007/dcr.0b013e3181cdb243

Cited by 128 publications

(87 citation statements)

References 9 publications

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“…The presence of free fluid without perforation is a risk factor of treatment failure, and we Table 5. Published studies continued to exclude patients who presented with this condition (22). In this sense, we think the classification proposed by Ambrosetti et al (18) is the simplest and allows more accurate selection of patients who will benefit most from outpatient treatment.…”

Section: Stagingmentioning

confidence: 99%

Outpatient treatment in uncomplicated acute diverticulitis: 5-year experience

Moya

Bellón²,

Arroyo³

et al. 2016

Turk J Gastroenterol

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Section: Stagingmentioning

confidence: 99%

Outpatient treatment in uncomplicated acute diverticulitis: 5-year experience

Moya

Bellón²,

Arroyo³

et al. 2016

Turk J Gastroenterol

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“…It usually has an uncomplicated course, manifesting primarily as pain; however, some patients may have abscesses, fistulas, obstruction, and/or perforation at presentation. Acute diverticulitis imposes an important clinical burden on health care systems, resulting in more than 300 000 hospital admissions and $2.5 billion in cost annually (1,2). Computed tomography (CT) of the abdomen is often the diagnostic test of choice, with sensitivity, specificity, and positive and negative predictive values all well greater than 95%.…”

Section: Study Eligibility and Selectionmentioning

confidence: 99%

Colonoscopy after CT Diagnosis of Diverticulitis to Exclude Colon Cancer: A Systematic Literature Review

Sai¹,

Velayos²,

Neuhaus³

et al. 2012

Radiology

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Purpose:To estimate the prevalence of underlying adenocarcinoma of the colon in patients in whom acute diverticulitis was diagnosed at computed tomography (CT) and to compare that to the prevalence of colon cancer in the general population. Materials and Methods:A comprehensive literature review was performed to find articles in which patients with CT diagnosis of acute diverticulitis underwent surgery, colonoscopy, or barium enema study within 24 weeks. Patients meeting these criteria were included for analysis. A pooled prevalence of cancer was calculated on the basis of a random effects model and compared qualitatively with the prevalence of cancer in the general population. The 95% confidence intervals around the prevalence of cancer in the study populations were determined. Results:Ten articles met the inclusion criteria. Data from these articles included only 771 patients who underwent surgery, colonoscopy, or barium enema study within 24 weeks of diagnosis. Fourteen patients were found to have colon cancer, for a prevalence of 2.1% (95% confidence interval: 1.2%, 3.2%). This compares to a calculated estimated prevalence of 0.68% among U.S. adults older than 55 years.

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“…[33] In fact, as demonstrated in the DIVER trial, the frequency of perforation nearly halves with each subsequent episode, from 25% in the first episode to 12% with the second to 6% with the third and to 1% with further episodes. [34] Other factors, such as age, severity of the disease, immunocompromising co-morbidities, family history, or extent of the involved colon have not been clearly proven as risk factors for recurrence.…”

Section: Outcomes and Follow-up Recurrencementioning

confidence: 96%