Ovarian Abnormalities

McCue, Patrick M.

doi:10.1016/b978-0-7216-0252-3.50017-5

Cited by 9 publications

(16 citation statements)

References 28 publications

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“…While changes in the oestrus cycle have been documented in aged mares with PPID (McCue ), changes in fertility of stallions with PPID are unknown, due to low numbers of reports of PPID in stallions. In a previous case report, a 20‐year‐old Thoroughbred stallion showed no changes in fertility prior to diagnosis of PPID using ODST, CT and histopathology (Hatazoe et al .…”

Section: Discussionmentioning

confidence: 99%

Large pituitary adenoma in an 8‐year‐old Arabian stallion

Madrigal

Andrews

Rademacher

et al. 2016

Equine Veterinary Education

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Summary An 8‐year‐old Arabian stallion weighing 361 kg presented to Louisiana State University Veterinary Teaching Hospital with a 3‐month history of weight loss, exercise intolerance, long hair coat and recent history of seizures and aimless wandering in the pasture. An initial presumptive diagnosis of pituitary pars intermedia dysfunction (PPID) was made based on clinical signs. The initial examination revealed weight loss and loss of body condition (BCS 3/9), hypertrichosis, muscle wasting and reluctance to move when prompted. A neurological examination revealed dull mentation with no evidence of proprioceptive deficits in the limbs. Mild hyperglycaemia and a stress leucogram were noted on initial biochemical panel and haematology, respectively. Plasma adrenocorticotrophic hormone (ACTH) concentrations before and after thyrotropin releasing hormone (TRH) stimulation were markedly increased. Rapid slice computed tomography (CT) scan of the head before and after contrast revealed a large mass in the region of the pituitary gland suggestive of macroadenoma causing PPID. Prior to imaging, treatment consisted of supportive nursing care. Due to size of the pituitary gland (measuring 4.6 × 4.6 × 3.8 cm) and the presence of seizure‐like activity and dull mentation, the stallion was subjected to euthanasia. A necropsy was not performed. Pituitary macroadenomas in horses affected with PPID, who show neurological signs such as seizure‐like activity, dull mentation and aimless wandering, might have a poor prognosis and treatment with pergolide mesylate might not reduce pituitary gland size or relieve clinical signs. A CT scan is indicated in horses with neurological signs suspected of PPID to further evaluate pituitary gland size and surrounding structures and rule out other causes to better assess prognosis.

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Section: Discussionmentioning

confidence: 99%

Large pituitary adenoma in an 8‐year‐old Arabian stallion

Madrigal

Andrews

Rademacher

et al. 2016

Equine Veterinary Education

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“…They are almost always unilateral, slow‐growing and benign. Transrectal ultrasonography of a GCT often shows it to be multicystic, but the tumour may also appear as a solid mass or as a single large cyst (Daels and Hughes 1992; McCue 2007b). GCTs may develop during gestation.…”

Section: Ovarian Pathologiesmentioning

confidence: 99%

“…Teratomas are benign while dysgerminomas are malignant. The normal treatment is a surgical removal (McCue 2007b).…”

Section: Ovarian Pathologiesmentioning

confidence: 99%

Ovarian Ultrasonography in the Mare

Miró

2012

Reprod Domestic Animals

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Ultrasonography has become indispensable in the control of equine reproduction. Mare ovary layers are inverted with respect to other species, with the follicles and corpus luteum found inside the ovary; only large follicles protrude from the organ's surface. This renders the making of diagnoses via rectal palpation of the ovaries very difficult. Ultrasound imaging, however, provides another avenue of examination. Since its first use in 1980, the diagnostic potential of ultrasonography has greatly improved. Colour Doppler ultrasonography can even asses blood flow, allowing for much better monitoring of ovarian activity. This study discusses the use of ultrasound, and in particular colour Doppler ultrasonography, in the monitoring of mare ovarian function and disease.

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“…PPID is a clinical syndrome of aged horses associated with hirsutism, delayed molting, poor hair coat, laminitis, polyuria and polydipsia, and so on [ 8 ]. PPID in female Thoroughbreds can become a serious economic problem, since broodmares with PPID are reported to become subfertile [ 5 , 6 ]. On the other hand, male reproductive dysfunction induced by PPID has never been reported.…”

mentioning

confidence: 99%

“…Broodmares with PPID present abnormal estrous cycles, heat restraint, and low fertility. These symptoms could be induced by the unusual release of sex hormones in association with the decreased secretion of dopamine and a hypothalamo-pituitary system affected by an enlarged intermediate lobe [ 6 , 8 ]. Although reports on PPID of stallions is lacking, gonadotropic hormone released from the anterior lobe may affect the male genital system and reproductive behavior as well as the testicles.…”

mentioning

confidence: 99%

Pituitary pars intermedia dysfunction (equine Cushing’s disease) in a Thoroughbred stallion: a single report

Hatazoe

Kawaguchi

Hobo

et al. 2015

JES

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Equine pituitary pars intermedia dysfunction (PPID) generally occurs in older horses showing hirsutism, delayed molting, weight loss, polydipsia, polyuria, laminitis, and reproductive disorders (in broodmares), but there have been no reports on stallions. This report presents a case of a 21-year-old Thoroughbred stallion that developed hirsutism and experienced delayed molting. There were no abnormal findings for semen quality or the stallion’s sexual desire. The horse was diagnosed with PPID based on dexamethasone suppression test and plasma levels of adrenocorticotropic hormone. It was then medicated with pergolide mesylate. Since the horse died due to humerus fracture, an autopsy was conducted, and pituitary adenoma was confirmed. No pathological findings were defined in the testicles; therefore, reproductive activity might not have been impaired.

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Ovarian Abnormalities

Cited by 9 publications

References 28 publications

Large pituitary adenoma in an 8‐year‐old Arabian stallion

Large pituitary adenoma in an 8‐year‐old Arabian stallion

Ovarian Ultrasonography in the Mare

Pituitary pars intermedia dysfunction (equine Cushing’s disease) in a Thoroughbred stallion: a single report

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