Ovarian Fibroma with Serous Cystadenoma—An Unusual Combination: A Case Report

Abstract

Surface epithelial tumors account for more than 90% of ovarian tumors, of which serous tumors comprise 46%. Sex-cord stromal tumors constitute 8% of ovarian tumors, fibroma being the commonest, comprising 70% in this category. Combination of different types of tumors can occur in ovary with most common being Mucinous cystadenoma and Brenner tumour. We report a case of a very rare combination of ovarian tumour-Fibroma with Serous cystadenoma of the ovary. This combination is not mentioned in any standard textbooks or reference books of gynaecologic pathology. Extensive search of the English Literature showed only one reported case with this combination of ovarian tumors. To the best of our knowledge, this is the second case to be reported in English Literature.

A Collision between Fibroma and Serous Ovarian Cystadenoma Mimicking Carcinoma

“…Serous cystadenofibroma: blending epithelial and fibrous component. 3 In our case, there was a clear distinction between the fibrous solid and the serous cystic part, macroscopically and histologically.…”

“…Despite the fact that collision tumors have been recently increasingly reported, occurrence of these tumors with the ovary is rare, especially in the collision of two benign variants. 3,4 Surface epithelial-stromal tumors are the commonest of ovarian tumors. Sex cord stromal tumors are less common.…”

“…A few papillary excrescences may be present. 3 I report a rare collision between two benign tumors -solid and cystic, fibroma and serous cystadenoma of the ovary. This collision between two benign tumors is a diagnostic challenge imitating a malignant ovarian tumor.…”

Bilateral synchronous benign ovarian neoplasm: A rare occurrence

“…[7] Common combinations with ovarian tumours include mucinous cystadenoma and a combination of Brenner tumour, mature cystic teratoma, Sertoli-Leidig cell tumour may be seen. [8] Ovarian tumours are currently classified based on the histogenesis of the ovary. Early development of the ovary is characterised by segregation and migration of the primordial germ cells from their sites of origin to the genital ridges (bilateral thickenings of the coelomic epithelium).…”

Suspecting the unsuspected in a large adnexal mass in a postmenopausal woman

“…Heterologous elements and a combination of these tumours with other ovarian tumors have been variously reported in literature. 12,13 In the background of paucity of literature, a high suspicion of such variants while dealing with ovarian tumors would be desirable.…”