Ovarian Non-Hodgkin Lymphoma Revealed by Bone Metastasis: A Rare Pediatric Case

Abstract

Ovary involvement of non-Hodgkin lymphoma (NHL) is rare. We report a rare case of ovarian NHL during adolescence revealed by bone metastasis. The diagnosis of malignant lymphoma was established after adnexectomy and histological study of the excised tissue. The tumor was classified as a diffuse large B-cell lymphoma. The patient has been treated according to the LMB French protocol with good outcome after two years. Although NHL is a rare ovarian neoplasm, it is essential to establish an accurate diagnosis as early as possible for therapeutic purposes.

Diffuse Large B-cell Lymphoma of the Ovaries Presenting With a Paraneoplastic Sclerotic Skin Lesion

“…Lymphomas of the ovary in the pediatric population are extremely rare occurrences. They can be primary or secondary, with the latter presenting in the setting of widely disseminated disease or as a presenting feature of extra-ovarian disease [ 9 , 10 ]. NHL primarily involving the ovary is even rarer with scant literature review available, limited to case reports.…”