Ovarian teratoma in a teenager causing ureterohydronephrosis

Abstract

Rationale: Teratomas are solid tumors that may occur in both gonadal and extragonadal locations, depending on the age of the child. Benign cystic teratomas are relatively common tumors among women of reproductive age, but they can occur at any age. The clinical presentation is not specific. They can be found incidentally when patients are investigated for other conditions or they can present as emergencies when the ovarian teratoma is torsioned or ruptured. Patient concerns: We present the case of a 17-year-old adolescent girl that was seen in our emergency department on several occasions for recurrent episodes of abdominal pain ongoing for 6 months. Diagnosis: An ultrasonography (US) was performed as an outpatient and a left ovarian mass was found along with right ureterohydronephrosis (UHN). Further assessment of the mass was done by abdominal and pelvic CT and tumoral markers. CT appearance was more suggestive of a teratoma. Interventions: She underwent laparotomy with complete excision of the tumor. Outcome: The patient had an uneventful recovery. A renal US follow up showed reduction of the dilatation, demonstrating that the condition was secondary to tumor compression. Lessons: In a teenager with nonspecific symptoms, a high suspicion index for tumors is mandatory. An early diagnosis and management avoid complications like UHN.

Giant mature ovarian teratoma case report

“…The mechanisms of ovarian parthenogenetic activation have not been fully clarified; however, a relationship with mutation of the proto-oncogene c-mos has been reported. As many as 30% of c-mos knockout mice develop ovarian teratomas, another theory explains teratomas is abnormal differentiation of fetal germ cells that originate from the fetal yolk sac [1,7] . Clinical presentation is usually asymptomatic, but it can manifest as an abdominal pain in 70-80% of cases or as a mass in lower abdomen.…”

“…Clinical presentation is usually asymptomatic, but it can manifest as an abdominal pain in 70-80% of cases or as a mass in lower abdomen. Indeed, nearby organs can be affected or compressed if the tumor grows to very large sizes which lead to difficulty in distinguishing the diagnosis [5,1] . In note, 60% of mature teratomas are between 5-10 cm while, only 10% of it are larger than 15 cm [8] .…”

“…Surgical intervention is the main choice for mature teratoma management due to it encapsulated and non-invasion structure [2] . Since the majority of mature teratoma are children and adolescent, it is essential to aim toward conservation ovarian surgery to prevent any puberty disorder [1] .…”

“…The word "teratomas" is delivered from the Greek language (which the word terato means "a monster" and onkoma means "mass or swelling") [1] . Teratomas are germ cell tumours (GCT) that derive from germ layers which are: ectoderm, mesoderm and endoderm [2] .…”

Ovarian Teratomas in Children and Adolescents: Our Own Experience and Review of Literature

“…The word “Teratomas” has its roots in Greek language, since it comes from Greek “terato”, which means monster, and the word “onkoma”, which means “mass or swelling” [ 4 ]. These tumours are embryonal neoplasms, where two or three germ layers are present [ 5 ].…”