Overactive bladder syndrome and bladder wall thickness in patients with obstructive sleep apnea syndrome

Abstract

ObjectiveThe main objective of the present study was to evaluate the presence of overactive bladder (OAB) syndrome, nocturia, urgency, and urge incontinence in patients with obstructive sleep apnea syndrome (OSAS), and measure bladder wall thickness (BWT) in these patients.Materials and MethodsThe patient group was composed of 38 patients with OSAS. The control group was composed of 15 healthy individuals. All patients were evaluated using the Epworth Sleepiness Scale (ESS) and Overactive Bladder Symptom Score (OABSS). The bladder wall thickness was measured by transabdominal ultrasound (US). The presence of nocturia, urinary urgency, and urge incontinence were also evaluated.ResultsThe mean OABSS was significantly higher in the patient group compared with the control group (p=0.048). The minimum oxygen saturation (Min.SO2) of patients with urgency was found to be significantly lower (p=0.014). The time spent below 90% of oxygen saturation (SO2) was significantly longer in patients with urinary urgency (p=0.009). There was no difference in BWT measurements between the patient group and the control group. There was a significant relationship between BWT values and OABSS in patients with OSAS (p=0.002).ConclusionThe results of the present study suggest that OSAS is associated with OAB syndrome. As a key symptom of OAB, urgency correlates with hypoxia in cases with OSAS. Although the present study did not observe any difference in BWT measurements between the patients and the control group, there was a correlation between BWT measurements and OABSS in patients with OSAS.

Troubles urinaires et génito-sexuels dans le syndrome d’apnée obstructive du sommeil : revue de la littérature

“…Contrairement à la nycturie que les patients expérimentent exclusivement durant la nuit, l'HAV se manifeste aussi pendant la journée (23). Des altérations multifactorielles, hypoxémiques, psychiques, nerveuses, hormonales et/ou vasculaires ont été suggérées entrainant la destruction nerveuse, la dénervation du detrusor et l'altération du métabolisme de la sérotonine (24).…”

“…L'incontinence urinaire était détectée chez 39,6% des femmes ayant une HAV. Ils ont observé que le traitement du SAOS par CPAP pendant 3 mois chez 111 femmes souffrant d'HAV, a permis une amélioration statistiquement significative des scores de l'hyperactivité vésicale (OABSS) et l'incontinence urinaire (ICIQ-SF) chez les patientes ayant un SAOS modéré à sévère (p<0,01)(23,24,32). Cependant des études supplémentaires comparatives sont nécessaire pour définir les meilleures stratégies thérapeutiques de l'HAV associée au SAOS(23).Données urodynamiquesQuelques études urodynamiques ont évalué l'évolution des données urodynamiques après traitement par CPAP, chez les patients souffrant de SAOS.…”

The predictive factors of nocturia in young Asian adult males: an online survey

“…Obesity increased intra-abdominal pressure and led to nocturia 15 . In addition, those with obesity had a higher chance of obstructive sleep apnea, which resulted in nocturnal polyuria and detrusor instability 16 , 17 . One supportive evidence in this study was that the participants with nocturia had a higher IPSS (except times of nocturnal voiding) score, especially with regards to the storage scores.…”

Nocturia and Sleep: Focus on Common Comorbidities and Their Association with Obstructive Sleep Apnea

“…Severity of OSA was proportional to OAB and urinary incontinence occurrence [50]. A diluted nocturnal urine was predictive of OSA diagnosis, with 88% of sensitivity in patients with daytime OAB symptoms [51], which were more severe in the OSA group than in the control group [52]. Proposed mechanisms for the aforementioned relationship include the intermittent hypoxia induced by OSA; this oxidative stress changes the bladder structurally and functionally [53].…”

“…Proposed mechanisms for the aforementioned relationship include the intermittent hypoxia induced by OSA; this oxidative stress changes the bladder structurally and functionally [53]. Indeed, bladder-wall thickness and OAB symptoms were closely related in OSA patients [52]. However, one study found no increased prevalence of OAB, nocturia, or urgent urinary incontinence symptoms in young male patients with OSA [54].…”