2023
DOI: 10.1007/s44174-023-00087-8
|View full text |Cite
|
Sign up to set email alerts
|

Overcoming Challenges and Innovations in Orthopedic Prosthesis Design: An Interdisciplinary Perspective

Pranav G. Kulkarni,
Namuna Paudel,
Shilpa Magar
et al.

Abstract: Recent advances in the orthopedic prostheses design have significantly improved the quality of life for individuals with orthopedic disabilities. However, there are still critical challenges that need to be addressed to further enhance the functionality of orthopedic prostheses improving biocompatibility to promote better integration with natural tissues, enhancing durability to withstand the demands of daily use, and improving sensory feedback for better control of movement are the most pressing issues. To ad… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1
1

Citation Types

0
15
0

Year Published

2023
2023
2024
2024

Publication Types

Select...
6
1

Relationship

0
7

Authors

Journals

citations
Cited by 29 publications
(15 citation statements)
references
References 78 publications
0
15
0
Order By: Relevance
“…[ 73 ] We anticipate that the HA@Cur@Ag hydrogel will undergo continuous enhancement through multidisciplinary collaboration, enabling its application in a broader range of clinical disease models, such as osteoarthritis, rheumatoid arthritis, and peri‐arthroprosthesis infection. [ 74 ]…”
Section: Discussionmentioning
confidence: 99%
“…[ 73 ] We anticipate that the HA@Cur@Ag hydrogel will undergo continuous enhancement through multidisciplinary collaboration, enabling its application in a broader range of clinical disease models, such as osteoarthritis, rheumatoid arthritis, and peri‐arthroprosthesis infection. [ 74 ]…”
Section: Discussionmentioning
confidence: 99%
“…In addition, angiogenesis is crucial in the wound healing process as sufficient nutrients must be transported to the newly formed granulation tissue by blood vessels. [31] We analyzed IHC staining for VEGF, which is a representative angiogenetic marker expressed by endothelial cells to measure the healing status in proliferation phase. As shown in Figure 5i, it shows that the PVDF + US group has the deepest staining.…”
Section: Immunohistochemical (Ihc) Staining and Quantificationmentioning
confidence: 99%
“…Thus, there is a contradiction between the cytocompatibility (suitability for cell growth) and printability of a bioink. [11][12][13] In the early stages of 3D bioprinting, researchers often mixed high-strength biomaterials with high-cytocompatibility biomaterials to achieve both properties. 11 But this resulted in greater negative effects on cell growth due to the presence of high-viscosity and high-strength materials, Fig.…”
Section: Introductionmentioning
confidence: 99%
“…Thus, there is a contradiction between the cytocompatibility (suitability for cell growth) and printability of a bioink. 11–13…”
Section: Introductionmentioning
confidence: 99%