Overoxidized polypyrrole/graphene nanocomposite with good electrochemical performance as novel electrode material for the detection of adenine and guanine

Gao, Yansha; Xu, Jingkun; Lu, Limin; Wu, Liping; Zhang, Kaixin; Nie, Tao; Zhu, Xiaofei; Wu, Yao

doi:10.1016/j.bios.2014.06.044

Cited by 144 publications

(45 citation statements)

References 35 publications

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“…Most conducting polymer/graphene composites have excellent electrical conductivity. Gao et al 32 developed electrochemically coated porous structure films of overoxidized polypyrrole/graphene (PPyox/GR) deposited onto GCE. This structure was successfully utilized as an efficient electrode material for the quantitative detection of adenine and guanine.…”

Section: Nonenzymatic Sensorsmentioning

confidence: 99%

Electrochemical Sensors and Biosensors Based on Nanomaterials and Nanostructures

et al. 2014

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Section: Nonenzymatic Sensorsmentioning

confidence: 99%

Electrochemical Sensors and Biosensors Based on Nanomaterials and Nanostructures

et al. 2014

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“…Reduced graphene oxide (RGO) is the chemically reduced form of GO. RGOs possess improved electrical conductivity, and could be applied for the functionalization of desired biomolecules [ 29 , 30 , 31 , 32 ]. The main problem now is how to make an evenly dispersed graphene derivative that exhibits its proper performance in the fabrication process for a biosensor.…”

Section: Introductionmentioning

confidence: 99%

Detection of Guanine and Adenine Using an Aminated Reduced Graphene Oxide Functional Membrane-Modified Glassy Carbon Electrode

Yang

Xiao

et al. 2017

Sensors

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A new electrochemical sensor based on a Nafion, aminated reduced graphene oxide and chitosan functional membrane-modified glassy carbon electrode was proposed for the simultaneous detection of adenine and guanine. Fourier transform-infrared spectrometry (FTIR), transmission electron microscopy (TEM), and electrochemical methods were utilized for the additional characterization of the membrane materials. The prepared electrode was utilized for the detection of guanine (G) and adenine (A). The anodic peak currents to G and A were linear in the concentrations ranging from 0.1 to 120 μM and 0.2 to 110 μM, respectively. The detection limits were found to be 0.1 μM and 0.2 μM, respectively. Moreover, the modified electrode could also be used to determine G and A in calf thymus DNA.

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“…With the development of nanobiotechnology, various nanocomposite materials based on observed synergistic effects have found widespread applications in the fields of biomaterials [1], drug delivery [2], and detection of molecules [3]. In addition to the special structure, electrochemical properties, and catalytic activity of graphene (GN), graphene oxide (GO), an oxidized derivative of GN, is rich with various oxygenated functional groups at its basal plane and edges, including hydroxide, epoxide, carbonyl, and carboxyl groups [4,5].…”

Section: Introductionmentioning

confidence: 99%

One-Step Electrosynthesis of Graphene Oxide-Doped Polypyrrole Nanocomposite as a Nanointerface for Electrochemical Impedance Detection of Cell Adhesion and Proliferation Using Two Approaches

2016

Journal of Nanomaterials

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A novel nanointerface of graphene oxide-doped polypyrrole (GO/PPy) is prepared on the surface of an indium tin oxide (ITO) electrode for electrochemical impedance detection of cell adhesion and proliferation through a facile one-step electropolymerization. The prepared GO/PPy nanocomposite had a robust surface and provided a biocompatible substrate for A549 cells adhesion and proliferation. The adhesion and proliferation of A549 cells on the surface of the GO/PPy modified ITO electrode directly increased the electron transfer resistance of [Fe(CN)6]3−/4−redox probe and influenced the impedance properties of the GO/PPy modified ITO electrode system. Based on these results, the adhesion and proliferation of A549 cells could be detected by electrochemical impedance technology using two approaches. Therefore, the present paper confirms that the GO/PPy nanocomposite film provides an excellent biological-electrical interface for cell immobilization and offers advantages of simple, low-cost fabrication and multiparameter detection and possesses potential application in cytological studies.

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Overoxidized polypyrrole/graphene nanocomposite with good electrochemical performance as novel electrode material for the detection of adenine and guanine

Cited by 144 publications

References 35 publications

Electrochemical Sensors and Biosensors Based on Nanomaterials and Nanostructures

Electrochemical Sensors and Biosensors Based on Nanomaterials and Nanostructures

Detection of Guanine and Adenine Using an Aminated Reduced Graphene Oxide Functional Membrane-Modified Glassy Carbon Electrode

One-Step Electrosynthesis of Graphene Oxide-Doped Polypyrrole Nanocomposite as a Nanointerface for Electrochemical Impedance Detection of Cell Adhesion and Proliferation Using Two Approaches

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