The gravitational wave event, GW190521, is the most massive binary black hole merger observed by ground-based gravitational wave observatories LIGO/Virgo to date. While the observed gravitational wave signal is mainly in the merger and ringdown phases, the inspiral gravitational wave signal of the GW190521-like binary will be more visible to space-based detectors in the low-frequency band. In addition, the ringdown gravitational wave signal will be louder in the next generation (3G) of ground-based detectors in the high-frequency band, displaying the great potential of multiband gravitational wave observations. In this paper, we explore the scientific potential of multiband observations of GW190521-like binaries with a milli-Hz gravitational wave observatory: LISA; a deci-Hz observatory: B-DECIGO; and (next generation of) hecto-Hz observatories: aLIGO and ET. In the case of quasicircular evolution, the triple-band observations of LISA, B-DECIGO, and ET will provide parameter estimation errors of the masses and spin amplitudes of component black holes at the level of order of 1–10%. This would allow consistency tests of general relativity in the strong field at an unparalleled precision, particularly with the “B-DECIGO + ET” observation. In the case of eccentric evolution, the multiband signal-to-noise ratio found in “B-DECIGO + ET” observation would be larger than 100 for a five-year observation prior to coalescence, even with high final eccentricities.