Overweight and obesity may play a role in the pathogenesis of chronic spontaneous urticaria

Zbiciak-Nylec, Martyna; Wcisło‐Dziadecka, Dominika; Kasprzyk, Marta; Kulig, Andrzej; Laszczak, J.; Noworyta, M.; Adamus, S.; Brzeźińska-Wcisło, Ligia; Rogala, Barbara; Brzoza, Zenon

doi:10.1111/ced.13368

Cited by 34 publications

(22 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…a BMI over 30 kg m −2 and the aggravation of CSU lesions after initiation of OMZ. The link between obesity and CSU has already been suggested in two previous studies 3,4 . The proportion of patients who were obese was significantly higher in the nonresponder group.…”

Section: Patients Characteristics Total Responders Nonresponders P‐vasupporting

confidence: 54%

Clinical predictive factors of unresponsiveness to omalizumab in patients with chronic spontaneous urticaria

et al. 2020

View full text Add to dashboard Cite

show abstract

Section: Patients Characteristics Total Responders Nonresponders P‐vasupporting

confidence: 54%

Clinical predictive factors of unresponsiveness to omalizumab in patients with chronic spontaneous urticaria

et al. 2020

View full text Add to dashboard Cite

show abstract

“…Our study also revealed that the incidence of ur caria was more among the pa ents who were overweight or obese which is also in accordance with other several studies 6,19 previously. This may be due to the fact that there are several evidences that prove obesity has been associated 20 with chronic low grade inflamma on and due to this obese person has decreased immune tolerance to an gens hence increasing the chances of allergies and other immune diseases due to the shi of balance towards T helper 2 21profile.…”

Section: Resultssupporting

confidence: 93%

Association of Obesity with Chronic Idiopathic Urticaria at Birat Medical College and Teaching Hospital

Choudhary

Shrestha

2020

Birat J. Health Sci.

View full text Add to dashboard Cite

Introduction: A frequent association between metabolic syndrome with chronic idiopathic urticaria has been suggested by many studies but thorough investigations about the influence of obesity and overweight on chronic spontaneous urticaria has not been done. Objectives: To find out the association of obesity with chronic idiopathic urticaria. Methodology: Patients with chronic idiopathic urticaria were assessed for the body weight, height, body mass index, age of disease onset and duration of the disease. Results: A total of 151 patients were enrolled in the study and among them 64 % were females as compared to 26 % males. The age of the patients included ranged from 17 years to 77 years. Among the patients included in study, 69 % of the patients suffering from CIU were found to be overweight and obese. The body mass index of the patient included ranged from 16.7 to 34.2 with mean of 24.3+/-4.3. Conclusion: There is a relatively high incidence of urticaria among the people who are obese and overweight.

show abstract

“…Several risk factors such as the presence of autoantibodies, age older than 45 years, and vitamin D deficiency have been reported to be associated with longer duration of CSU [4][5][6][7] . A study of 85 CSU patients in Poland revealed that higher BMI values had a trend towards longer disease duration 8 .…”

mentioning

confidence: 99%

“…Zbiciak-Nylec et al 8 firstly reported that higher BMI values had a trend towards longer disease duration. In this study, we further revealed that higher WC rather than higher BMI is more related with the longer disease duration of CSU, although both WC and BMI can affect the disease duration.…”

mentioning

confidence: 99%

High waist circumference rather than high body mass index may be a predictive risk factor for the longer disease duration of chronic spontaneous urticaria

Kim

Han

Bang

et al. 2021

Sci Rep

View full text Add to dashboard Cite

In a previous study, we found that higher waist circumference (WC) and higher body mass index (BMI) both increase the risk of chronic spontaneous urticaria (CSU). The aim of this study was to determine whether WC and BMI also increase the duration of CSU. We used multivariable Cox proportional hazards models to determine the hazard ratio (HR) for longer disease duration (longer than 3 years) according to WC and BMI. A total of 52,667 subjects were enrolled and their mean age was 54.5. After adjustments for other confounding variables the high WC/high BMI group had 1.062 times higher HR (95% CI, 1.028–1.098) than the normal WC/normal BMI group. Interestingly, the high WC/normal BMI group showed a significantly higher HR (1.053; 95% CI, 1.008–1.101) than the normal WC/normal BMI group, but not the normal WC/high BMI group (0.998; 95% CI, 0.951–1.046). Taken together, our results suggest that high WC rather than high BMI is a predictive risk factor for the longer disease duration of CSU.

show abstract

Overweight and obesity may play a role in the pathogenesis of chronic spontaneous urticaria

Cited by 34 publications

References 23 publications

Clinical predictive factors of unresponsiveness to omalizumab in patients with chronic spontaneous urticaria

Clinical predictive factors of unresponsiveness to omalizumab in patients with chronic spontaneous urticaria

Association of Obesity with Chronic Idiopathic Urticaria at Birat Medical College and Teaching Hospital

High waist circumference rather than high body mass index may be a predictive risk factor for the longer disease duration of chronic spontaneous urticaria

Contact Info

Product

Resources

About