2011
DOI: 10.1159/000327688
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Overweight Is an Additional Prognostic Factor in Acute Pancreatitis: A Meta-Analysis

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Cited by 59 publications
(26 citation statements)
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“…16,21 Several tests can help differentiate biliary pancreatitis from other causes of pancreatitis, such as aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, and serum bilirubin, 22 which are the standard liver function tests and should be reviewed before making a confident diagnosis. 27 We noticed that body weight can predict the clinical severity of AP with significant P value (P = 0.009; Table 2). 22,23 Notably, the incidence of AP is increasing, paralleled with an increase in the prevalence of obesity.…”
Section: Discussionmentioning
confidence: 86%
“…16,21 Several tests can help differentiate biliary pancreatitis from other causes of pancreatitis, such as aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, and serum bilirubin, 22 which are the standard liver function tests and should be reviewed before making a confident diagnosis. 27 We noticed that body weight can predict the clinical severity of AP with significant P value (P = 0.009; Table 2). 22,23 Notably, the incidence of AP is increasing, paralleled with an increase in the prevalence of obesity.…”
Section: Discussionmentioning
confidence: 86%
“…4 The association of visceral fat and poor outcomes may originate from its propensity to release cytokines and its necrosis predisposing to pseudocyst and acute fluid collection formation, particularly when the necrotic region becomes infected and may therefore lead to an increased risk of local complications. 8 , 20 The study by O'Leary, however, did not find any association between visceral fat volume and increased local complications. 13 What is not clear from these reports, however, is the potential for confounding factors such as comorbidities related to obesity-associated metabolic syndrome, hypertension and diabetes, which were not routinely evaluated and may have an impact on outcome.…”
Section: Discussionmentioning
confidence: 94%
“…Several independent studies have also confirmed this observation [4][5][6]. Visceral obesity, which is a component of metabolic syndrome, has been recognized to have a stronger correlation with poor outcomes in patients with AP [1][2][3][4][5][6][7]. NAFLD is an objective marker of visceral obesity.…”
Section: Introductionmentioning
confidence: 81%
“…Results from meta-analysis show that obesity (defined as BMI>30) was associated with significantly higher incidence of systemic and local complication and higher rate of mortality from AP [1][2][3]. Several independent studies have also confirmed this observation [4][5][6].…”
Section: Introductionmentioning
confidence: 83%