Overweight, obesity and gastric cancer risk: Results from a meta-analysis of cohort studies

Yang, Ping; Zhou, Yong; Chen, Bo; Wan, Hang; Ge, Jia; Bai, Hai-Long; Wu, Xiaoting

doi:10.1016/j.ejca.2009.04.019

Cited by 315 publications

(226 citation statements)

References 60 publications

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“…The association between BMI and gastric cancer risk has been explored in many previous studies, and recently a meta-analysis reported that overweight and obesity were positively associated with risk of GCCs and overall gastric cancer but not with risk of GNCCs (13). However, the number of included studies (n ¼ 10) and cases (n ¼ 9,492) was relatively smaller, and many a few important studies were not included.…”

Section: Discussionmentioning

confidence: 99%

Body Mass Index and Risk of Gastric Cancer: A Meta-analysis of a Population with More Than Ten Million from 24 Prospective Studies

Chen

Liu

Wang

et al. 2013

Cancer Epidemiology, Biomarkers &Amp; Prevention

199

143

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Background: To provide a quantitative assessment of the association between body mass index (BMI) and the risk of gastric cancer, we summarized the evidence from prospective studies.Methods: Eligible studies published up to November 30, 2012, were retrieved via computer searches of MEDLINE and EMBASE as well as manual review of references. Summary relative risks (SRR) with their corresponding 95% confidence intervals (CI) were calculated using a random-effects model.Results: A total of 24 prospective studies of BMI and gastric cancer risk with 41,791 cases were included in our analysis. Overall, both overweight (BMI, 25-30 kg/m

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Section: Discussionmentioning

confidence: 99%

Body Mass Index and Risk of Gastric Cancer: A Meta-analysis of a Population with More Than Ten Million from 24 Prospective Studies

Chen

Liu

Wang

et al. 2013

Cancer Epidemiology, Biomarkers &Amp; Prevention

199

143

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“…Metabolic syndrome and insulin resistance have been associated with increased risk of cancer, including cardia gastric cancers (42,43). This is mediated by adipokines and cytokines released by metabolically active visceral fat, which result in chronic hyperinsulinemia and increase risk of insulin-like growth factormediated carcinonogenesis (44).…”

Section: Mechanism Of Actionmentioning

confidence: 99%

Physical Activity Is Associated with Reduced Risk of Gastric Cancer: A Systematic Review and Meta-analysis

Singh

Varayil

Devanna

et al. 2014

Cancer Prevention Research

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Physical activity may be associated with reduced risk of gastric cancer. We performed a systematic review and meta-analysis to evaluate the magnitude of the association and the quality of supporting evidence. After a comprehensive search of bibliographic databases and conference proceedings through February 2013 for observational studies that examined associations between recreational and/or occupational physical activity and gastric cancer risk, we identified 16 studies (seven cohort, nine case control) reporting 11,111 cases of gastric cancer among 1,606,760 patients. Summary adjusted-OR estimates with 95% confidence intervals (CI) were estimated using the random-effects model. Meta-analysis demonstrated that the risk of gastric cancer was 21% lower among the most physically active people as compared with the least physically active people (OR ¼ 0.79; 95% CI, 0.71-0.87) with moderate heterogeneity among studies (I 2 ¼ 55%). This protective effect was seen for gastric cancers in the cardia (four studies; OR ¼ 0.80; 95% CI, 0.63-1.00) and distal stomach (five studies; OR ¼ 0.63; 95% CI, 0.52-0.76). The effect size was significantly smaller in highquality studies (six studies; OR ¼ 0.86; 95% CI, 0.75-0.99), as compared with low-quality studies (10 studies; OR ¼ 0.74; 95% CI, 0.69-0.81). The results were consistent across sex, study quality, study design, and geographic location. In conclusion, meta-analysis of published observational studies indicates that physical activity is associated with reduced risk of gastric cancer. Lifestyle interventions focusing on increasing physical activity may decrease the global burden of gastric cancer, in addition to a myriad of other health benefits. Cancer Prev Res; 7(1); 12-22. Ó2013 AACR.

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“…3 Obesity is a major predisposing factor for type II diabetes, dyslipidemia, hypertension, cardiovascular diseases, metabolic syndrome and certain cancers. [4][5][6][7] World Health Organization stated approximately there were 400 million adults who were obese in 2005 in which the rates are higher among women. 8 The prevalence of obesity had increased in the Arabian Gulf region because of the economic rise happened between the year 1970 and 1980 and it was really alarming all the national health authorities.…”

Section: Introductionmentioning

confidence: 99%

A cross-sectional study on prevalence of obesity and its association with dietary habits among college students in Abha, Saudi Arabia

Alshahrani

Sujatha

2017

Int J Community Med Public Health

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Background: During the past few years there was a western influence in the kingdom of Saudi Arabia and as a result of it the eating habits among the male college students had rapidly changed which also increased the prevalence rate of overweight and obesity. Therefore the objectives of the study were 1) To determine the prevalence of overweight and obesity in a sample of male college students in Abha, Saudi Arabia. 2) To determine the relationship between the Student’s body weight and their eating habits. Methods: A cross-Sectional study was done among 445 male college students from king Khalid University, Abha Saudi Arabia. Study participants were selected randomly and self-administered questionnaire was used to collect the data. Data was analyzed by using the statistical package for social sciences (SPSS Inc. version 16.) and expressed in percentages. Results: The study found that 28% and 20 % of students were overweight and obese. Daily intake of snacks and lack of consumption of vegetable and fruits were found to be the common dietary habits among the male college students. Majority of the students were aware about the balanced nutrition and it was positively correlated with the normal body weight. Conclusions: The current study suggest involvement of college Administration and family members will further reduce the burden of overweight and obesity among college students in the nation.

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Overweight, obesity and gastric cancer risk: Results from a meta-analysis of cohort studies

Cited by 315 publications

References 60 publications

Body Mass Index and Risk of Gastric Cancer: A Meta-analysis of a Population with More Than Ten Million from 24 Prospective Studies

Body Mass Index and Risk of Gastric Cancer: A Meta-analysis of a Population with More Than Ten Million from 24 Prospective Studies

Physical Activity Is Associated with Reduced Risk of Gastric Cancer: A Systematic Review and Meta-analysis

A cross-sectional study on prevalence of obesity and its association with dietary habits among college students in Abha, Saudi Arabia

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