Overwhelming Underuse of Bisphosphonates in French Nursing Home Residents After Proximal Femoral Fracture

Floch, P Le; Kermarrec, P; Gentric, A.

doi:10.1007/s12603-019-1169-y

Cited by 4 publications

(2 citation statements)

References 18 publications

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“…The treatment patterns observed in this study are broadly aligned with the results of other studies conducted across different countries (United States [ 20 , 21 ]; China, Hong Kong, Singapore, South Korea, Malaysia, Taiwan, and Thailand [ 22 ]; Korea [ 21 ]; Spain [ 21 ]; and the UK [ 23 ]), which found that bisphosphonates were the most commonly used drug category after osteoporotic fracture. Additionally, studies conducted in India [ 24 ], Italy [ 25 ], and France [ 26 ] observed that vitamin D 3 was frequently prescribed to patients after fracture, although the literature regarding vitamin D 3 supplementation patterns post-fracture is limited. Moreover, in agreement with our findings, bisphosphonates and active vitamin D 3 were the most commonly prescribed treatments after hip and vertebral fracture in a recent analysis of health insurance claims in Japan [ 27 ].…”

Section: Discussionmentioning

confidence: 99%

A real-world study of treatment patterns among patients with osteoporotic fracture: analysis of a Japanese hospital database

Hagino

Yoshinaga²,

Hamaya³

et al. 2023

Arch Osteoporos

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Summary Health records of patients hospitalized for osteoporotic fracture were analyzed. Prior to the index hospital admission, most patients were not receiving any antiosteoporotic treatment. During the index hospitalization visit, 25.5% of patients received antiosteoporotic treatment. The most common treatment regimens were active vitamin D3, bisphosphonates, and teriparatide. Purpose To examine the real-world treatment patterns and factors associated with receipt of treatment among Japanese patients with osteoporotic fracture. Methods We retrospectively analyzed health records of patients who were hospitalized for osteoporotic fracture between February 2016 and February 2018 in Japan. The type and duration of treatment with antiosteoporotic medications prescribed during hospital stays and after discharge were examined using descriptive statistics. Demographic and clinical factors (e.g., age, previous diagnoses, Charlson Comorbidity Index scores) associated with osteoporotic treatment were explored using multivariable logistic regression. Results A total of 112,275 patient medical records were evaluated, including 56,574 records from patients with hip fracture, 26,681 records from patients with vertebrae fracture, and 29,020 patients with non-vertebral non-hip fractures. Prior to the index hospital admission, most patients (91.7%, n = 102,919) were not receiving any antiosteoporotic treatment. For those receiving treatment, active vitamin D3 (51.1%, n = 4778) and bisphosphonates (47.5%, n = 4441) were the most common. During the index hospitalization visit, 25.5% (n = 28,678) of patients received treatment for their fracture, including active vitamin D3 (n = 17,074), bisphosphonates (n = 10,007), and teriparatide (n = 4561). Upon discharge, 41.5% (n = 46,536) of patients returned to their home and 34.3% (n = 38,542) of patients were transferred to a different hospital or medical care facility. Variables associated with receipt of treatment at follow-up included older age, previous diagnoses of osteoporosis and fracture, and higher Charlson Comorbidity Index scores. Conclusion Despite osteoporotic fracture being a major health concern within older Japanese populations, treatment with antiosteoporotic medication regimens remains generally low.

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Section: Discussionmentioning

confidence: 99%

A real-world study of treatment patterns among patients with osteoporotic fracture: analysis of a Japanese hospital database

Hagino

Yoshinaga²,

Hamaya³

et al. 2023

Arch Osteoporos

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“…Patients' QOL level after intervention was assessed by World Health Organization Quality of Life (WHOQOL)-BREF [ 16 ] from the aspects of psychology, physiology, environment, and social relations, and the score of each domain was obtained by the mean score of item of such domain multiplied by 4, with higher scores indicating better QOL. Cronbach's α coefficient of WHOQOL-BREF was 0.90, the Guttman split-half reliability coefficient was 0.86, and Cronbach's α coefficients in the field of physiology, psychology, society, and environment were, respectively, 0.74, 0.72, 0.72, and 0.87.…”

Section: Methodsmentioning

confidence: 99%

Effect of Combining Operating Room Nursing Based on Clinical Quantitative Assessment with WeChat Health Education on Postoperative Complications and Quality of Life of Femoral Fracture Patients Undergoing Internal Fixation

Liu

Wang

Han

et al. 2022

Journal of Healthcare Engineering

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Objective. To explore the effect of combining operating room nursing based on clinical quantitative assessment with WeChat health education on postoperative complications and quality of life (QOL) of femoral fracture patients undergoing internal fixation. Methods. Ninety femoral fracture patients treated in our hospital (July 2018 to July 2021) were chosen as the research objects and split into the control group (routine intervention) and the study group (combination of operating room nursing based on clinical quantitative assessment and WeChat health education) according to the nursing intervention modes, with 45 cases each. After nursing, the postoperative complications and QOL of patients were compared between the two groups. Results. No statistical between-group differences in general data were observed ( P > 0.05); the hospital stay, weight-bearing time, and fracture healing time were obviously shorter in the study group than in the control group ( P < 0.05); 1 d after surgery, the VAS pain status was not significantly different between the two groups ( P > 0.05), and 2 d and 3 d after surgery, the VAS scores were significantly lower in the study group than in the control group ( P < 0.05); 1 d after surgery, the Harris scores of patients in the two groups were close and did not present statistical difference ( P > 0.05), and 8 weeks after surgery, the Harris score was significantly higher in the study group than in the control group ( P < 0.05); the scores on self-care agency such as self-concept, self-care skills, sense of self-care responsibility, and health knowledge level were significantly higher in the study group than in the control group ( P < 0.05); compared with the control group, the probability of occurring incision infection, lung infection, pressure sore, swelling and pain, and other complications was significantly lower in the study group ( P < 0.05). Conclusion. Implementing operating room nursing based on clinical quantitative assessment combined with WeChat health education to femoral fracture patients undergoing internal fixation can effectively improve their postoperative clinical indicators, reduce their postoperative pain sensation and complication incidence, and effectively promote the joint motion range, which is conducive to enhancing their self-care agency and QOL.

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What is a reasonable rate for specific osteoporosis drug therapy in older fragility fracture patients?

et al. 2020

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Overwhelming Underuse of Bisphosphonates in French Nursing Home Residents After Proximal Femoral Fracture

Cited by 4 publications

References 18 publications

A real-world study of treatment patterns among patients with osteoporotic fracture: analysis of a Japanese hospital database

A real-world study of treatment patterns among patients with osteoporotic fracture: analysis of a Japanese hospital database

Effect of Combining Operating Room Nursing Based on Clinical Quantitative Assessment with WeChat Health Education on Postoperative Complications and Quality of Life of Femoral Fracture Patients Undergoing Internal Fixation

What is a reasonable rate for specific osteoporosis drug therapy in older fragility fracture patients?

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