Oxalic Acid Mitigates Cadmium Toxicity in Cicer arietinum L. Germinating Seeds by Maintaining the Cellular Redox Homeostasis

Sakouhi, Lamia; Kharbech, Oussama; Massoud, Marouane Ben; Munemasa, Shintaro; Murata, Yoshiyuki; Chaoui, Abdelilah

doi:10.1007/s00344-021-10334-1

Cited by 21 publications

(18 citation statements)

References 68 publications

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“…1 indicate that Cd stress resulted in chickpea root and shoot growth delay in terms of FW. However, OA application counteracted this deleterious impact, which is consistent with our previous result (Sakouhi et al 2021b). The protective attributes of organic acids against MH injury were reported by recent investigations (El Rasafi et al 2020;Soyingbe et al 2020).…”

Section: Discussionsupporting

confidence: 93%

“…The protective attributes of organic acids against MH injury were reported by recent investigations (El Rasafi et al 2020;Soyingbe et al 2020). This effect should be attributed, at least in part, to the restriction of Cd 2+ accumulation in seedling tissues, as well as the protection of sensitive biomolecules, such as proteins from decarboxylation and membrane lipids from peroxidation (El Rasafi et al 2020;Sakouhi et al 2021b). Moreover, LMWOA, including OA, were suggested to be involved in the vacuolar sequestration of metal ions, limiting, thereby, their mobility within the cell (Kosakivska et al 2021).…”

Section: Discussionmentioning

confidence: 69%

Section: Introductionmentioning

confidence: 97%

“…Previously we reported that exogenous OA mitigates Cd toxicity in an important food legume, Cicer arietinum (Sakouhi et al 2021b). Exogenous application of OA decreases contents of oxidative stress markers (malondialdehyde and protein carbonyls) and improves glutathione and NAD(P) H redox state (Sakouhi et al 2021b). However, the involvement of the major lipid-derived aldehyde 4-HNE, Noxs, antioxidant enzymes, and PM H + -ATPase in OA-triggered Cd tolerance has not been investigated.…”

Section: Introductionmentioning

confidence: 97%

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Exogenous Oxalic Acid Protects Germinating Chickpea Seeds Against Cadmium Injury

Sakouhi

Kharbech

Massoud

et al. 2021

J Soil Sci Plant Nutr

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The objective of the present study was to elucidate the mechanism by which oxalic acid (OA) alleviates cadmium (Cd) stress. Chickpea (Cicer arietinum L.) seeds were treated with 200 µM CdCl 2 for 6 days or 3 days followed by the combination 200 µM Cd + 100 µM OA for three additional days. Exogenous OA mitigated the growth inhibition by Cd of both roots and shoots. This positive effect can be attributed to the increased OA exudation from roots and the alleviation of the Cdinduced depletion of endogenous OA in shoots (80% increase versus Cd-stressed). The combination Cd + OA proved to be effective in protecting cell membrane integrity. This beneficial effect was reflected by 36 and 24% decrease in lipoxygenase (LOX) activity in roots and shoots, respectively, and 60% decrease in the accumulation of the harmful aldehyde, 4-hydroxy-2-nonenal (4-HNE) in roots when compared to Cd-treated samples. Besides, OA restored the Cd-imposed disruption of the plasma membrane function. This effect was depicted by an optimal H + -ATPase activity and proton exudation rate. Oxalic acid counteracted the Cd-induced overproduction of hydroxyl radical (OH•) and NADPH-oxidase activity increase, leading to restore a steady cellular redox state. Furthermore, OA modulated the impact of Cd on Cu/Zn-superoxide dismutase (Cu/ Zn-SOD), ascorbate peroxidase (APX), and catalase (CAT) activities in chickpea seedlings. Present results indicate that OA is able to alleviate Cd toxicity by protecting plasma membrane integrity and modulating antioxidant activities. Moreover, our findings shed light on the interplay between plasma membrane H + -ATPase and the accumulation and root exudation of OA.

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Section: Discussionsupporting

confidence: 93%

Section: Discussionmentioning

confidence: 69%

Section: Introductionmentioning

confidence: 97%

Section: Introductionmentioning

confidence: 97%

See 2 more Smart Citations

Exogenous Oxalic Acid Protects Germinating Chickpea Seeds Against Cadmium Injury

Sakouhi

Kharbech

Massoud

et al. 2021

J Soil Sci Plant Nutr

Self Cite

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show abstract

“…The strong affinity to the binding of heavy metals is due to the electronegativity of functions in these molecules; in particular carboxyl groups (-COO-). This is the case with EDTA [17] and organic acids (malic, oxalic, citric, benzoic) [1,18,19].…”

Section: Mcda000695 8(4)2021mentioning

confidence: 99%

Chemicals Mitigate Copper Toxicity on Seed Germination and Plant Growth

Massoud

2021

MCDA

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Assessing the Potential Role of Zinc Oxide Nanoparticles for Mitigating Cadmium Toxicity in Capsicum annuum L. Under In Vitro Conditions

Karmous

Gammoudi

Chaoui³

2022

J Plant Growth Regul

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Oxalic Acid Mitigates Cadmium Toxicity in Cicer arietinum L. Germinating Seeds by Maintaining the Cellular Redox Homeostasis

Cited by 21 publications

References 68 publications

Exogenous Oxalic Acid Protects Germinating Chickpea Seeds Against Cadmium Injury

Exogenous Oxalic Acid Protects Germinating Chickpea Seeds Against Cadmium Injury

Chemicals Mitigate Copper Toxicity on Seed Germination and Plant Growth

Assessing the Potential Role of Zinc Oxide Nanoparticles for Mitigating Cadmium Toxicity in Capsicum annuum L. Under In Vitro Conditions

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