Oxcarbazépine et syndrome DRESS : un cas pédiatrique révélé par une hépatite fulminante

Bosdure, E.; Cano, Aline; Roquelaure, Bertrand; Reynaud, Rachel; Boyer, M.; Viard, L.; Sarles, J.

doi:10.1016/j.arcped.2004.05.018

Cited by 36 publications

(8 citation statements)

References 8 publications

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“…DRESS has been initially described as the anticonvulsant hypersensitivity syndrome (11). This syndrome is rarely seen in childhood even though a large number of children receive anticonvulsant treatment (12). Here we report two unique cases of infants under two months of age, whose finding upshots were consistent with DRESS syndrome due to phenobarbital usage.…”

Section: Dress (Drug Rash With Eosinophilia and Systemicsupporting

confidence: 60%

“…DRESS syndrome has no age or sex tendency; nevertheless, this syndrome is rarely seen in childhood even though a large number of children get anticonvulsant treatment (12,16). In one review article, the mean age of patients diagnosed with DRESS syndrome was 40.7 and the average age of cases resulting in death was 49 years; however there were no differences for demographic and clinical variables between cases who died and those that resolved (5).…”

Section: Discussionmentioning

confidence: 99%

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Drug Rash With Eosinophilia and Systemic Symptoms Syndrome in Infancy: A Report of Two Rare Cases

et al. 2013

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Section: Dress (Drug Rash With Eosinophilia and Systemicsupporting

confidence: 60%

Section: Discussionmentioning

confidence: 99%

Drug Rash With Eosinophilia and Systemic Symptoms Syndrome in Infancy: A Report of Two Rare Cases

et al. 2013

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“…DRESS syndrome (drug related rash with eosinophilia and systemic symptoms) and granulomatosis are less frequently reported in literature (70). Oxcarbamazepine can induce liver toxicity, generally included in systemic toxicity, like Stevens-Johnson syndrome (71). …”

Section: Resultsmentioning

confidence: 99%

Liver Illness and Psychiatric Patients

et al. 2016

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Patients with psychiatric disorders are usually more exposed to multiple somatic illnesses, including liver diseases. Specific links are established between psychiatric disorders and alcohol hepatitis, hepatitis B, and hepatitis C in the population as a whole, and specifically in drug abusers. Metabolic syndrome criteria, and associated steatosis or non-alcoholic steato-hepatitis (NASH) are frequent in patients with chronic psychiatric disorders under psychotropic drugs, and should be screened. Some psychiatric medications, such as neuroleptics, mood stabilizers, and a few antidepressants, are often associated with drug-induced liver injury (DILI). In patients with advanced chronic liver diseases, the prescription of some specific psychiatric treatments should be avoided. Psychiatric disorders can be a limiting factor in the decision-making and following up for liver transplantation.

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“…In children, it is yet probably underestimated because the diagnosis is difficult. Eleven cases of DRESS syndrome have been reported in five years in the United States from 1995 to 2000 [6]. For some authors, age would be a factor favoring the occurrence of side effects and they are very important as age increases [7].…”

Section: Discussionmentioning

confidence: 99%

Severe Drug Eruption in Guinea Conakry

Cissé¹,

Tounkara²,

Diané³

et al. 2014

JCDSA

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Severe drug reactions are defined as mucocutaneous complications secondary to systemic administration of drugs likely to be life threatening. Our work was designed to determine the evolutio- 33%). The lethality rate was 9.09% (2/22) in the Stevens-Johnson syndrome and 53.85% (7/13) in the Toxic Epidermal Necrolysis. HIV infection was found in 17.95% (7/26) of our patients and 71.42% (5/7) of the deceased. The drug accountability was established in 79.48%; the most commonly implicated drugs in the Toxic Epidermal Necrolysis were sulfonamides followed by ARVs (nevirapine) and anti TB (isoniazid); in the SJS sulfonamides followed by salts of quinine and anti TB, the only case of DRESS was due to quinine. No drug was found in 20.52% (8 cases). HIV infection remains a poor prognostic factor. Our study shows the scarcity of Drug Rash with Eosinophilia and Systemic Symptoms and Acute generalized exanthematous pustulosis in our service.

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Oxcarbazépine et syndrome DRESS : un cas pédiatrique révélé par une hépatite fulminante

Cited by 36 publications

References 8 publications

Drug Rash With Eosinophilia and Systemic Symptoms Syndrome in Infancy: A Report of Two Rare Cases

Drug Rash With Eosinophilia and Systemic Symptoms Syndrome in Infancy: A Report of Two Rare Cases

Liver Illness and Psychiatric Patients

Severe Drug Eruption in Guinea Conakry

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