Oxcarbazepine monotherapy in carbamazepine-unresponsive trigeminal neuralgia

Gómez-Argüelles, J.M.; Dorado, Rodolfo; Sepulveda, J.; Herrera, Antonio; Arrojo, F. Gilo; Aragón, Eric; Huete, C. Ruiz; Terrón, C.; Anciones, B

doi:10.1016/j.jocn.2007.04.010

Cited by 70 publications

(38 citation statements)

References 27 publications

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“…[5] Various methods to synthesize these compounds have been reported in the literature. [6] Nevertheless, the development of new and efficient procedures for the selective synthesis of these seven-membered rings continues to represent an important and challenging goal.…”

mentioning

confidence: 99%

Palladium‐Catalyzed Reaction of Aryl Iodides with ortho‐Bromoanilines and Norbornene/Norbornadiene: Unexpected Formation of Dibenzoazepine Derivatives

et al. 2011

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mentioning

confidence: 99%

Palladium‐Catalyzed Reaction of Aryl Iodides with ortho‐Bromoanilines and Norbornene/Norbornadiene: Unexpected Formation of Dibenzoazepine Derivatives

et al. 2011

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“…OXC is recommended in patients who do not respond to CBZ. Carrazana found that the evidence supporting the use of OXC for trigeminal neuralgia is strong [9,10]. The use of OXC for other indications such as painful diabetic neuropathy, post-herpetic neuralgia, painful paroxysmal symptoms in multiple sclerosis, tremor, and migraine has already been investigated with a poor-moderate evidence level [5,[11][12][13][14].…”

Section: Discussionmentioning

confidence: 99%

A Retrospective Study: The Off-Label Use of Anticonvulsants at a Private Hospital in Indonesia

Rahajeng

Ikawati

Andayani

et al. 2018

Int J Pharm Pharm Sci

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Objective: Anticonvulsant is one class of drugs often used off-label. This study was conducted to investigate the prevalence and the indication of the off-label use of anticonvulsants in a private hospital in Java, Indonesia. Methods:This was an observational study with a retrospective data collection in a private hospital in Java. Data were obtained on the prescription of anticonvulsants. Indications of the use of anticonvulsants were obtained from the medical records of patients who were prescribed anticonvulsants. The off-label use of anticonvulsants was defined a prescribing of medication outside the indication approved by The National Agency of Drug and Food Control Indonesia (NA-DFC). The use off-label of anticonvulsants was calculated by descriptive analysis and presented as a percentage.Results: It showed that in one year there were 5,310 for 1,316 patients: of this 462 patients (35.11%) were for an off-label use. The anticonvulsants used off-label were oxcarbazepine 67.27% (37/55), carbamazepine 46.15% (54/117), pregabalin45.45% (60/132), phenytoin37.62% (225/598), valproate 25.34% (37/109), and gabapentin 18.28% (49/219). The highest off-label use of anticonvulsants was found in neurological and psychiatric disorders 67.32% (n=311), and on 97.19% of them were not supported by strong clinical evidence. Conclusion:The off-label use of anticonvulsants occurred in one-third of patients receiving prescriptions of anticonvulsants, even though for most of them there was a lack of evidence. More attention must be paid to the efficacy and risk of side effects of the drug used.

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“…С 1962 года и по настоящее время карбамазепин и его ана-логи (окскарбазепин, финлепсин, тегретол) являются препара-тами первой линии в лечении НТН [177,220,250,255,269,402,404,418,419,429,433]. За этот период накоплен большой опыт оценки эффективности и побочных явлений от длительного применения этого препарата.…”

Section: принципы лечения тригеминальной невралгииunclassified

Классическая Невралгия Тройничного Нерва

Балязина¹

2015

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Oxcarbazepine monotherapy in carbamazepine-unresponsive trigeminal neuralgia

Cited by 70 publications

References 27 publications

Palladium‐Catalyzed Reaction of Aryl Iodides with ortho‐Bromoanilines and Norbornene/Norbornadiene: Unexpected Formation of Dibenzoazepine Derivatives

Palladium‐Catalyzed Reaction of Aryl Iodides with ortho‐Bromoanilines and Norbornene/Norbornadiene: Unexpected Formation of Dibenzoazepine Derivatives

A Retrospective Study: The Off-Label Use of Anticonvulsants at a Private Hospital in Indonesia

Классическая Невралгия Тройничного Нерва

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