Oxidase-like activity of magnetically separable nano ceria for catechol detection

Yadav, Suraj V.; Rathod, Virendra K.

doi:10.1007/s42452-019-0971-9

Cited by 4 publications

(2 citation statements)

References 39 publications

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“…[8] Yadav et al (2019) chemically synthesized ceria magnetic nanoparticles for the detection of catechol. [9] Mishra et al (2016) showed peroxidase activity of green synthesized magnetic nanoparticles (prepared using banana peel extract) for glucose and hydrogen peroxide detection. [10] Liu et al (2015) reported that platinum NPs exhibited catechol oxidase like activity.…”

Section: Introductionmentioning

confidence: 99%

“…Biparva et al (2014) reported the peroxidase activity of zinc oxide (ZnO) NPs and used them for detection of carvedilol [8] . Yadav et al (2019) chemically synthesized ceria magnetic nanoparticles for the detection of catechol [9] . Mishra et al (2016) showed peroxidase activity of green synthesized magnetic nanoparticles (prepared using banana peel extract) for glucose and hydrogen peroxide detection [10] .…”

Section: Introductionmentioning

confidence: 99%

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Nanoparticles Mimicking Oxidase Activity and their Application in Synthesis of Neurodegenerative Therapeutic Drug L‐DOPA

et al. 2023

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Nanozymes are nanomaterials with intrinsic enzyme‐like activity and show high operational stability as compared to native enzymes. They have gathered the attention of researchers due to their unique physico‐chemical properties and diverse applications. In the present study, screening of different nanoparticles (zinc oxide, iron oxide, selenium and titanium oxide) was performed to evaluate their polyphenol oxidase (PPO) activity. PPO is a biotechnologically important enzyme and its application includes wastewater treatment, food processing and synthesis of l‐3,4‐dihydroxyphenylalanine (L‐dopa, a precursor of dopamine neurotransmitter). Out of all nanoparticles used in this study, zinc oxide nanoparticles (ZnO NPs) showed maximum enzyme activity of 75 %. ZnO NPs demonstrated high thermal stability and can be used upto 80°C. The colloidal solution of nanoparticles showed storage stability upto 6 months at room temperature and showed high activity in the pH range of 6–9 as compared to free enzyme. The nanoparticles were reused till 6th cycle retaining more than 80 % oxidase activity. To study its potential as a catalyst, it was used for the synthesis of L‐dopa from L‐tyrosine and a good productivity of 100 mg/L (0.1 g/L) was obtained. Thus, ZnO nanozymes can be used as an alternate to oxidase enzyme for synthesis of this therapeutic drug.

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Section: Introductionmentioning

confidence: 99%