1969
DOI: 10.1093/jee/62.2.483
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Oxidative Metabolism of C14-Labeled Baygon by Living House Flies and by House Fly Enzyme Preparations12

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Cited by 50 publications
(21 citation statements)
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“…The tubes were rinsed three additional times with 100 l of acetone, which was also spotted onto the TLC plate. The plates were developed twice in hexane:ethyl acetate:ethanol (35:6:5 by volume) as described by Shrivastava et al (1969). After drying for 4 h, the plates were exposed to Biomax MR-2 Þlm (Eastman Kodak, Rochester, NY) for 10 d at Ϫ80ЊC.…”
Section: Methodsmentioning
confidence: 99%
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“…The tubes were rinsed three additional times with 100 l of acetone, which was also spotted onto the TLC plate. The plates were developed twice in hexane:ethyl acetate:ethanol (35:6:5 by volume) as described by Shrivastava et al (1969). After drying for 4 h, the plates were exposed to Biomax MR-2 Þlm (Eastman Kodak, Rochester, NY) for 10 d at Ϫ80ЊC.…”
Section: Methodsmentioning
confidence: 99%
“…2-Isopropoxyphenol, an anticipated hydrolytic metabolite, is volatile, so it is possible that it was lost during the incubation, extraction, and separation processes. Alternatively, 2-isopropoxyphenol could have undergone complete decomposition as suggested by Shrivastava et al (1969). However, the amount of propoxur and its metabolites recovered from active cytosolic and non-NADPH microsomal fractions were not different from the boiled controls.…”
mentioning
confidence: 92%
“…5). Thus the isopropyl group of the carbamate, propoxur, is readily removed as acetone by the microsomal oxidase system of rats as well as several strains of houseflies (Oonnithan and Casida, 1968;Shrivastava et al, 1969); deisopropylation is a dominant feature of propoxur metabolism. The demethylation of one or both methyl groups of methoxychlor appears to be the basis for its biodegradability.…”
Section: 1 0- $- and N-alkyl Hydroxylationmentioning
confidence: 99%
“…6). N-Hydroxymethyl carbamates or their conjugates have been identified as metabolites of a number of carbamates in vivo and in microsomal oxidase systems of both mammals and insects (Hodgson and Casida, 1960;Oonnithan and Casida, 1968;Miyamoto et al, 1969;Shrivastava et al, 1969;Douch and Smith, 1971a,b;Strother, 1972). The corresponding Nde methylated metabolite is known in only a few cases (Douch and Smith, 1971 a) since N-unsubstituted carbamates may be extremely labile to hydrolysis (Fahmy et aI., 1966).…”
Section: 1 0- $- and N-alkyl Hydroxylationmentioning
confidence: 99%
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