Oxygen Delivery and Oxygen Uptake in Postoperative and Septic Patients

Vermeij, C. G.; Feenstra, B. W. A.; Bruining, H. A.

doi:10.1378/chest.98.2.415

Cited by 73 publications

(27 citation statements)

References 24 publications

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“…While some investigators demonstrated good agreement between the two methods [18,22], others noticed distinct differences [23,24]. Discrepancies between the two methods may be attributed to several factors.…”

Section: Discussionmentioning

confidence: 99%

Different dosages of dobutamine in septic shock patients: determining oxygen consumption with a metabolic monitor integrated in a ventilator

et al. 2000

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With a metabolic monitor integrated in a ventilator it was possible to carry out continuous monitoring of calorimetric data under clinical conditions. In contrast to previous studies using indirect calorimetry, this study showed a moderate correlation between VO2 and DO2 in septic patients using either method. The clinical relevance of this finding requires further investigation. Different factors (e. g. injectant temperature, pulmonary VO2) produced substantial differences between VO2,IC and VO2,Fick as previously shown.

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Section: Discussionmentioning

confidence: 99%

Different dosages of dobutamine in septic shock patients: determining oxygen consumption with a metabolic monitor integrated in a ventilator

et al. 2000

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“…The studies which addressed the issue of the dependence of VO 2 on DO 2 in sepsis syndrome and ARDS consistently demonstrated pathology supply dependency whenever VO2 was calculated [5,[9][10][11][12][13][14][15][16][17][18]. In contrast, when oxygen uptake was measured directly, VO 2 was usually not correlated with DO 2 either in sepsis syndrome or ARDS [16,[19][20][21]. In this study VO2 was systematically evaluated by calculation and direct measurement before and after volume loading.…”

Section: Discussionmentioning

confidence: 99%

“…Importantly this pathologic dependence as well as elevated blood lactate levels were believed to increase the mortality in sepsis syndrome and ARDS by reflecting occult cellular hypoxia [5]. Other investigators, who measured VO2 by indirect calorimetry either in ARDS or sepsis syndrome, failed to reproduce this pathologic dependence [16,[19][20][21] and/or disputed its prognostic significance [20,21]. These discrepancies could be explained by differences either in interventions used to alter DO 2 (oxygen "flux test"), or in the patient population with regard to diagnosis, delay before study and metabolic status.…”

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confidence: 99%

Significance of pathologic oxygen supply dependency in critically ill patients: Comparison between measured and calculated methods

et al. 1994

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“…Others have found the correlation between oxygen consumption determined by the Fick method and oxygen delivery was almost wholly due to mathematical coupling. It was possible to demonstrate a correlation in only two of 10 patients when analysis of respired gases was used although the Fick method had shown delivery-dependence of oxygen consumption [76]. The issue of linkage is, and will continue to be, a source of contention but it does not arise if delivery and consumption are measured by different methods.…”

Section: Linkagementioning

confidence: 99%