Ozone treatment in a wind tunnel for the reduction of airborne viruses in swine buildings

Vyskocil, Jonathan M.; Turgeon, Nathalie; Turgeon, Jean-Gabriel; Duchaine, Caroline

doi:10.1080/02786826.2020.1790495

Cited by 13 publications

(6 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…E. coli bacteriophages generally pose low risk to humans and require less biocontainment. Bacteriophages as models for human viruses have been extensively used in various workplace settings to understand the behavior of viruses under different experimental conditions ( 37 – 40 ), making them a feasible surrogate for SARS-CoV-2 in this study. Using a variety of nonpathogenic (to humans) bacteriophages with different features (e.g., enveloped and nonenveloped, RNA and DNA, single- and double-stranded) represents an additional line of investigation for future studies ( 36 ).…”

Section: Resultsmentioning

confidence: 99%

Quantitative Assessment of Viral Dispersion Associated with Respiratory Support Devices in a Simulated Critical Care Environment

Avari

Hiebert

Ryzynski

et al. 2021

Am J Respir Crit Care Med

View full text Add to dashboard Cite

Rationale: Patients with severe coronavirus disease (COVID-19) require supplemental oxygen and ventilatory support. It is unclear whether some respiratory support devices may increase the dispersion of infectious bioaerosols and thereby place healthcare workers at increased risk of infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Objectives: To quantitatively compare viral dispersion from invasive and noninvasive respiratory support modalities. Methods: This study used a simulated ICU room with a breathing-patient simulator exhaling nebulized bacteriophages from the lower respiratory tract with various respiratory support modalities: invasive ventilation (through an endotracheal tube with an inflated cuff connected to a mechanical ventilator), helmet ventilation with a positive end-expiratory pressure (PEEP) valve, noninvasive bilevel positive-pressure ventilation, nonrebreather face masks, high-flow nasal oxygen (HFNO), and nasal prongs. Measurements and Main Results: Invasive ventilation and helmet ventilation with a PEEP valve were associated with the lowest bacteriophage concentrations in the air, and HFNO and nasal prongs were associated with the highest concentrations. At the intubating position, bacteriophage concentrations associated with HFNO (2.66 × 10 4 plaque-forming units [PFU]/L of air sampled), nasal prongs (1.60 × 10 4 PFU/L of air sampled), nonrebreather face masks (7.87 × 10 2 PFU/L of air sampled), and bilevel positive airway pressure (1.91 × 10 2 PFU/L of air sampled) were significantly higher than those associated with invasive ventilation ( P < 0.05 for each). The difference between bacteriophage concentrations associated with helmet ventilation with a PEEP valve (4.29 × 10 –1 PFU/L of air sampled) and bacteriophage concentrations associated with invasive ventilation was not statistically significant. Conclusions: These findings highlight the potential differential risk of dispersing virus among respiratory support devices and the importance of appropriate infection prevention and control practices and personal protective equipment for healthcare workers when caring for patients with transmissible respiratory viral infections such as SARS-CoV-2.

show abstract

Section: Resultsmentioning

confidence: 99%

Quantitative Assessment of Viral Dispersion Associated with Respiratory Support Devices in a Simulated Critical Care Environment

Avari

Hiebert

Ryzynski

et al. 2021

Am J Respir Crit Care Med

View full text Add to dashboard Cite

show abstract

“…Van Doremalen et al [2] were uncertain whether virus transmission through contaminated surfaces or aerosols was viable for 3 h. However, virus viability depends on antibiotic conditions, such as humidity (>90% RH). Adequate disinfection with maximum antiviral efficacy cannot be achieved with a humidity <50% [6,[26][27][28]. During the in-situ experiments conducted in ambulances, humidity was found to be <90% (55-75% RH), which could account for the detection of SARS-related coronaviruses.…”

Section: Discussionmentioning

confidence: 99%

Ozone Efficacy for the Disinfection of Ambulances Used to Transport Patients during the COVID-19 Pandemic in Peru

Gómez-Castillo,

Rivera Romero,

Reátegui-Ochoa

et al. 2023

IJERPH

View full text Add to dashboard Cite

We assessed the disinfection efficacy of an ozone generator prototype in ambulances used to transport patients with coronavirus disease (COVID-19). This research consisted of three stages: in vitro tests using microbial indicators, such as Candida albicans, Escherichia coli, Staphylococcus aureus and Salmonella phage, which were experimentally inoculated onto polystyrene crystal surfaces within a 23 m3 enclosure. They were then exposed to ozone at a 25 ppm concentration using the ozone generator (Tecnofood SAC) portable prototype, and the decimal reduction time (D) was estimated for each indicator. The second stage involved the experimental inoculation of the same microbial indicators on a variety of surfaces inside conventional ambulances. The third stage consisted of exploratory field testing in ambulances used to transport patients with suspected COVID-19. During the second and third stages, samples were collected by swabbing different surfaces before and after 25 ppm ozonisation for 30 min. Results suggested that ozone was most effective on Candida albicans (D = 2.65 min), followed by Escherichia coli (D = 3.14 min), Salmonella phage (D = 5.01 min) and Staphylococcus aureus (D = 5.40 min). Up to 5% of the microbes survived following ozonisation of conventional ambulances. Of the 126 surface samples collected from ambulances transporting patients with COVID-19, 7 were positive (5.6%) for SARS-related coronavirus as determined on reverse transcription quantitative real-time polymerase chain reaction (RT-qPCR). Ozone exposure from the ozone generator prototype inside ambulances at a concentration of 25 ppm for 30 min can eliminate gram positive and negative bacteria, yeasts, and viruses.

show abstract

“…In fact, the ozone and UV can destroy the viruses and bacteria easily [19][20][21]. Also, other techniques as cold plasma or non-thermal plasma (NTP) and photocatalytic oxidation can be recommended.…”

Section: Engineering Methods To Treat Air Emitted By Healthcare Settingsmentioning

confidence: 99%

Improvement of indoor air quality in healthcare settings during COVID-19 pandemic (Preprint)

Lakhouit¹,

Hachimi²,

Mokhi³

et al. 2020

Preprint

View full text Add to dashboard Cite

UNSTRUCTURED This study investigates the importance of using engineering ventilation in healthcare settings, especially during widespread disease outbreaks such as COVID-19. Ventilation can be used to improve indoor air quality in care homes, hospitals, and quarantine locations. Although there are several different types of engineering ventilation, mechanical ventilation is most suitable for reducing the impact and spread of COVID-19 in healthcare and other facilities. However, this ventilation mode should be designed according to the American Society of Heating, Refrigerating and Air-Conditioning Engineers (ASHRAE), with the minimum exhaust air flow measuring 5 liters per second per square meter.

show abstract

Ozone treatment in a wind tunnel for the reduction of airborne viruses in swine buildings

Cited by 13 publications

References 23 publications

Quantitative Assessment of Viral Dispersion Associated with Respiratory Support Devices in a Simulated Critical Care Environment

Quantitative Assessment of Viral Dispersion Associated with Respiratory Support Devices in a Simulated Critical Care Environment

Ozone Efficacy for the Disinfection of Ambulances Used to Transport Patients during the COVID-19 Pandemic in Peru

Improvement of indoor air quality in healthcare settings during COVID-19 pandemic (Preprint)

Contact Info

Product

Resources

About