P.7.b.011 First episode psychosis during adolescence: clinical and therapeutic differences from adulthood onset

Garcia, M. Villar; Ilzarbe, D.; Mansilla, S.; Vilaplana-Pérez, Alba; Fàbrega, Marina Geli i; Parellada, Eduard; Sugranyes, Gisela; Baeza, I.

doi:10.1016/s0924-977x(13)70943-x

Cited by 2 publications

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“…A esquizofrenia e outras psicoses frequentemente se apresentam na infância e adolescência com impactos significativos no funcionamento psicossocial e na qualidade de Brazilian Journal of Health Review, Curitiba, v. 6, n. 6, p.30933-30942, nov./dec., 2023 vida. A psicose de início precoce, antes dos 18 anos de idade, é considerada um transtorno mais grave do que a psicose na idade adulta e é acompanhada por um nível mais alto de sintomas negativos e inespecíficos com pior prognóstico, sintomas depressivos importantes e alta taxa de mortalidade (García et al, 2013;Xia et al, 2018).…”

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Psicose puerperal na adolescência

Bezerra,

Silva,

De Oliveira

et al. 2023

Braz. J. Hea. Rev.

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A psicose puerperal ou pós-parto é um transtorno de humor raro que se manifesta durante ou em até 4 semanas após o parto, sob forma de delírios e alucinações e é considerada uma emergência psiquiátrica. O quadro, ao surgir antes dos 18 anos de idade, é considerado um transtorno psiquiátrico grave com pior prognóstico, além de impactar significativamente no desenvolvimento psicossocial e na qualidade de vida. O objetivo do trabalho é realizar um relato de caso de psicose puerperal em uma adolescente atendida em uma Unidade Básica de Saúde (UBS) em parceria com o Ambulatório de Psiquiatria da Infância e Adolescência no Agreste de Pernambuco. O caso relatado é de uma puérpera de 14 anos de idade com sintomas persecutórios, delírios, agressividade, insônia e tentativa de suicídio. Após acompanhamento psiquiátrico e manejo terapêutico a paciente apresenta melhora dos sintomas e evolução satisfatória do quadro, porém aguarda liberação de psicoterapia pelo serviço público de saúde.

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Section: Introductionunclassified

Psicose puerperal na adolescência

Bezerra,

Silva,

De Oliveira

et al. 2023

Braz. J. Hea. Rev.

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“…S chizophrenia and other psychoses often present in childhood and adolescence with consequent impairments in psychosocial functioning and quality of life. Early-onset psychosis (EOP, age of onset before 18 years) is considered a more severe disorder than adult-onset psychosis and is accompanied by a higher level of negative and nonspecific symptoms (García et al 2013 ). Patients with EOP have a poor prognosis, severe depressive symptoms, and a high death rate (Ropcke and Eggers 2005 ; Remschmidt et al 2007 ).…”

Section: Introductionmentioning

confidence: 99%

Olanzapine Versus Risperidone in Children and Adolescents with Psychosis: A Meta-Analysis of Randomized Controlled Trials

Xia

Liu

et al. 2018

Journal of Child and Adolescent Psychopharmacology

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Objective: To compare the efficacy and safety of olanzapine and risperidone in children and adolescents (aged ≤18 years) with psychosis by conducting a meta-analysis of randomized controlled trials (RCTs).Methods: Several English and Chinese databases were searched for studies published before February 8th, 2017. Two independent investigators screened the studies according to prespecified criteria and extracted the data. Review Manager 5.3 was used to conduct the data synthesis.Results: Eight RCTs involving 457 participants (225 participants in the olanzapine group and 232 participants in the risperidone group) were included. No significant differences were observed in the mean scores on the Positive and Negative Syndrome Scale/Brief Psychiatric Rating Scale (standard mean difference [SMD] = −0.06, 95% confidence intervals [CI] = [−0.31, 0.19], p = 0.63), the positive symptom scores (SMD = −0.09, 95% CI = [−0.32, 0.15], p = 0.48), or the negative symptom scores (SMD = −0.11 95% CI = [−0.34, 0.13], p = 0.38) between the two groups. Regarding adverse effects, the mean increases in weight (MD = 2.90, 95% CI = [1.41, 4.39], p = 0.0001), body mass index (MD = 0.90, 95% CI = [0.42, 1.38], p = 0.0003), and incidence of hypersomnia (risk ratios [RR] = 1.98, 95% CI = [1.15, 3.43], p = 0.01) were higher in the olanzapine group, while the incidence of insomnia (RR = 0.31, 95% CI = [0.11, 0.85], p = 0.02), prolactin elevation (RR = 0.11, 95% CI = [0.01, 0.85], p = 0.03), myotonia (RR = 0.12, 95% CI = [0.03, 0.49], p = 0.003), tremor (RR = 0.22, 95% CI = [0.08, 0.63], p = 0.005), and akathisia (RR = 0.27, 95% CI = [0.12, 0.57], p = 0.0007) was higher in the risperidone group.Conclusions: There is no significant difference in efficacy between olanzapine and risperidone for the treatment of children and adolescents with psychosis, but the side effect profiles of these two medications differ. High-quality RCTs are needed before recommending clinical treatment in children and adolescents.

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P.7.b.011 First episode psychosis during adolescence: clinical and therapeutic differences from adulthood onset

Cited by 2 publications

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Psicose puerperal na adolescência

Psicose puerperal na adolescência

Olanzapine Versus Risperidone in Children and Adolescents with Psychosis: A Meta-Analysis of Randomized Controlled Trials

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