P wave duration and dispersion in multiple sclerosis

Koçer, Abdülkadir; Karakaya, Osman; Kargın, Ramazan; Barutçu, İrfan; Esen, Ali Metin

doi:10.1007/s10286-005-0283-6

Cited by 10 publications

(6 citation statements)

References 23 publications

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“…1). 3 , 7–85 Fourteen of these articles utilized only a computer‐assisted technique for P‐wave evaluation.…”

Section: Resultsmentioning

confidence: 99%

Meta‐Analysis of P‐Wave Dispersion Values in Healthy Individuals: The Influence of Clinical Characteristics

Nussinovitch¹

2012

Noninvasive Electrocardiol

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Pd, Pmax, and Pmin span a wide range of values in healthy individuals. Seemingly, abnormal values were often reported in healthy adults. The high variability of P-wave parameters in healthy individuals, and overlapping of the results with those reported for patients with increased risk for atrial fibrillation, might suggest that this technique has limited sensitivity and specificity. The variability between studies may stem from methodological issues and, therefore, there is a definite need for methodological standardization of Pd measurements.

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“…1). 3 , 7–85 Fourteen of these articles utilized only a computer‐assisted technique for P‐wave evaluation.…”

Section: Resultsmentioning

confidence: 99%

Meta‐Analysis of P‐Wave Dispersion Values in Healthy Individuals: The Influence of Clinical Characteristics

Nussinovitch¹

2012

Noninvasive Electrocardiol

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“…The significance of an increased P wave duration and PDW in our patients is unknown. Kocer et al (2005) investigated P wave duration and dispersion in 31 MS patients and compared with 33 healthy subjects, their study showed that P wave duration and dispersion were prolonged significantly in MS patients compared to control subjects. We cannot find other studies which investigated P wave changes in MS patients.…”

Section: Discussionmentioning

confidence: 99%

P wave duration and dispersion and QT interval in multiple sclerosis

Razazian

Hedayati

Moradian

et al. 2014

Multiple Sclerosis and Related Disorders

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“…Some authors used conventional electrocardiographic (ECG) parameters to make statements about the autonomic dysfunction of the cardiovascular system. Significantly higher maximum P-wave duration and P-wave dispersion (risk factors for atrial fibrillation) were reported in 31 MS patients compared with 33 sex-and age-matched controls [23], and similar findings (along with a non-significant increase in QT interval) were reported from a study in 84 MS patients and 84 age-and sex-matched controls [24]. An Italian study in 31 relapsing-remitting MS (RRMS) patients reported that 16% had an increased QTc interval, which seemed to have a cerebral origin possibly driven by involvement of the insular cortex.…”

Section: Testing For Cad In Msmentioning

confidence: 93%

Cardiac Autonomic Dysfunction in Multiple Sclerosis: A Systematic Review of Current Knowledge and Impact of Immunotherapies

Findling

Hauer

Pezawas

et al. 2020

JCM

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Cardiac autonomic dysfunction (CAD) has been reported in patients with multiple sclerosis (MS). This systematic review summarizes the evidence for the types and prevalence of CAD in MS patients, as well as its association with MS type, disease characteristics, fatigue and immunotherapies used to treat MS. The analysis revealed that CAD is correlated with pathophysiological processes of MS, can trigger serious cardiovascular complications that may reduce life expectancy, and may have implications for treatment with immunotherapies, especially fingolimod. Numerous mainly small case-control or cohort studies have reported various measures of CAD (particularly heart rate variation) in MS patients, showing higher rates of abnormality versus controls. A smaller number of studies have reported on cardiac autonomic symptoms in MS, including orthostatic intolerance/dizziness in around 50% of patients. CAD also appears to be associated with disease duration and to be more common in progressive than relapsing-remitting MS. However, although a substantial evidence base suggests that assessing CAD in people with MS may be important, standardised methods to evaluate CAD in these patients have not yet been established. In addition, no studies have yet looked at whether treating CAD can reduce the burden of MS symptoms, disease activity or the rate of progression.

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P wave duration and dispersion in multiple sclerosis

Abstract: P wave duration and PWD was found to be statistically different in patients with MS and control subjects.

Cited by 10 publications

References 23 publications

Meta‐Analysis of P‐Wave Dispersion Values in Healthy Individuals: The Influence of Clinical Characteristics

Meta‐Analysis of P‐Wave Dispersion Values in Healthy Individuals: The Influence of Clinical Characteristics

P wave duration and dispersion and QT interval in multiple sclerosis

Cardiac Autonomic Dysfunction in Multiple Sclerosis: A Systematic Review of Current Knowledge and Impact of Immunotherapies

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