Abstract:than the usual dose for non-pigmented carcinomas (37 j/ cm 2 ) appears to be necessary to induce adequate photochemical reactions because melanine restricts the diffusion of red light in the deep layers of the epidermis, where lentigo maligna is known to be localized. We suggest that the therapeutic response is probably also related to direct cellular effects of MAL, a precursor of protoporphyrin IX, which is an endogen ligand of peripheral receptors for benzodiazepines, which are involved in cellular prolifer… Show more
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