P1.06-010 Analysis of the Incidence of Cancer Cachexia in Patients with Advanced Lung Cancer at Referral to a Dietitian

Hug, Adele; Phillips, Iain; Allan, Lindsey A.; Mendis, Jeewaka; Ezhil, Veni

doi:10.1016/j.jtho.2016.11.874

Cited by 1 publication

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“…As well as affecting QoL, weight loss appears to affect survival. In a retrospective assessment of more than 300 patients with lung cancer the authors have previously identified that more than 5% weight loss from usual body weight affected outcome, OS was 100 days less in those with more than 5% weight loss (188 vs. 299, P ¼ 0.0078) [11]. Weight loss was measured at the time of referral to the dietitian and not at diagnosis and the study was limited by a lack of consistent time of dietetic review.…”

Section: Key Pointsmentioning

confidence: 99%

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Dietetic assessment and intervention in lung cancer

Phillips

Hug

Allan

et al. 2019

Current Opinion in Supportive &Amp; Palliative Care

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Purpose of reviewSystemic therapy for lung cancer is increasing in intensity and duration. European nutrition guidelines suggest screening for weight loss and malnutrition, however acknowledges there is a lack of evidence. We discuss current data round this issue and identify opportunities for further research. Recent findingsInternational guidelines now exist to aid the definition of weight loss in cancer, including cachexia, sarcopenia and malnutrition. These allow consistent definition of overlapping, but distinct clinical syndromes. Nutritional status can be assessed in a range of ways including questionnaires, functional assessments, blood markers, physical activity, weight and BMI. Weight loss is commonly associated with a proinflammatory state. Future treatment is likely to be a combination of dietetic support and pharmacological treatment of cachexia. SummaryThere is a paucity of data on dietetic intervention. It is potentially quick, inexpensive and patient specific, using a holistic approach to aid patients who are malnourished or at risk of malnutrition. Lung cancerrelated weight loss is common, further strategies are needed to effectively assess and intervene. Dietetic intervention has the potential to improve patients' quality of life and outcomes.

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Section: Key Pointsmentioning

confidence: 99%

“…Cancer-related weight loss in this population is common and is likely to be multifactorial [11,12]. It may include at least three specific clinical syndromes: malnutrition, cachexia and sarcopenia.…”

Section: Introductionmentioning

confidence: 99%