P11.07: Vein of Galen aneurysm—a case report

Abstract

Lissencephaly is a rare disorder that is characterized by the disorganized and unlayered cortex. The cause of this disorder is related to chromosomal abnormalities and infection. The pathogenesis of lissencephaly is faulty migration of neuroblast. Lissencephaly is associated with Dandy-Walker syndrome and Miller-Dieker syndrome. A woman at 35 weeks of gestation was transferred to our hospital due to structural abnormality of fetal brain. Fetal brain showed ventricular dilation and decreased sulci in cerebral cortex on prenatal ultrasound examination and we diagnosed this case as lissencephaly. The baby was spontaneously delivered at 37 weeks 3 days of gestation and lissencephaly was confirmed by postnatal magnetic resonance imaging. Thrombosis of dural sinuses during fetal life is a rare finding. We report a case in which thrombosis of the dural sinuses was suspected on a routine ultrasound (US) scan performed at 22 weeks: in the occipital region a triangular sonolucent area with well defined borders was identified. This area corresponded to a dilatation of the posterior segment of the superior sagittal sinus, with interruption of the venous flow at that level within which a round echogenic mass without any vascular flow filling the posterior two thirds was identified. One week later, images compatible with the US diagnosis were obtained through magnetic resonance imaging (MRI) and confirmed the presence of a thrombus at the level of the torcula Herophilii. Monthly US scans were performed and no modifications of the thrombus dimensions were seen. A cesarean section was performed at term. Four days after delivery MRI confirmed the presence of a blood clot in the proximal right lateral dural sinus and torcula Herophilii. At 18 months the infant's neurodevelopmental assessment was normal. The good perinatal outcome of the case reported should be underlined on the set of information given to the parents in order to allow them to make a fully informed decision concerning termination versus letting the pregnancy to proceed. P11.06 Prenatal diagnosis of thrombosis of the dural sinuses P11.07 Vein of Galen aneurysm -a case report D. Pelinescu Onciul, R. Radulescu Botica Filantropia Clinical Hospital, RomaniaHerein we present the case of a 30 year old woman gravida 1, para 1, admitted at 29 weeks of gestation for US examination. At ultrasound scan we found that all biophysical parameters were in normal range for this gestational age. Morphologic appearance was normal excepting fetal cardiomegaly and a great aneurysm of the vein of Galen associated with hydrocephalus. Is an extremely rare abnormality, only around 400 cases being described. Laranjeiras Clínica Perinatal, BrazilLimb-body wall complex (LBWC) is a fetal malformation with the essential features of neural tube defects, body wall disruption and limb abnormalities. The diagnosis is made by the presence of at least two of the above features.In the present case of LBWC, the body defects were large, involving both the thorax and abdomen. The eviscerated organs form...