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Lissencephaly is a rare disorder that is characterized by the disorganized and unlayered cortex. The cause of this disorder is related to chromosomal abnormalities and infection. The pathogenesis of lissencephaly is faulty migration of neuroblast. Lissencephaly is associated with Dandy-Walker syndrome and Miller-Dieker syndrome. A woman at 35 weeks of gestation was transferred to our hospital due to structural abnormality of fetal brain. Fetal brain showed ventricular dilation and decreased sulci in cerebral cortex on prenatal ultrasound examination and we diagnosed this case as lissencephaly. The baby was spontaneously delivered at 37 weeks 3 days of gestation and lissencephaly was confirmed by postnatal magnetic resonance imaging. Thrombosis of dural sinuses during fetal life is a rare finding. We report a case in which thrombosis of the dural sinuses was suspected on a routine ultrasound (US) scan performed at 22 weeks: in the occipital region a triangular sonolucent area with well defined borders was identified. This area corresponded to a dilatation of the posterior segment of the superior sagittal sinus, with interruption of the venous flow at that level within which a round echogenic mass without any vascular flow filling the posterior two thirds was identified. One week later, images compatible with the US diagnosis were obtained through magnetic resonance imaging (MRI) and confirmed the presence of a thrombus at the level of the torcula Herophilii. Monthly US scans were performed and no modifications of the thrombus dimensions were seen. A cesarean section was performed at term. Four days after delivery MRI confirmed the presence of a blood clot in the proximal right lateral dural sinus and torcula Herophilii. At 18 months the infant's neurodevelopmental assessment was normal. The good perinatal outcome of the case reported should be underlined on the set of information given to the parents in order to allow them to make a fully informed decision concerning termination versus letting the pregnancy to proceed. P11.06 Prenatal diagnosis of thrombosis of the dural sinuses P11.07 Vein of Galen aneurysm -a case report D. Pelinescu Onciul, R. Radulescu Botica Filantropia Clinical Hospital, RomaniaHerein we present the case of a 30 year old woman gravida 1, para 1, admitted at 29 weeks of gestation for US examination. At ultrasound scan we found that all biophysical parameters were in normal range for this gestational age. Morphologic appearance was normal excepting fetal cardiomegaly and a great aneurysm of the vein of Galen associated with hydrocephalus. Is an extremely rare abnormality, only around 400 cases being described. Laranjeiras Clínica Perinatal, BrazilLimb-body wall complex (LBWC) is a fetal malformation with the essential features of neural tube defects, body wall disruption and limb abnormalities. The diagnosis is made by the presence of at least two of the above features.In the present case of LBWC, the body defects were large, involving both the thorax and abdomen. The eviscerated organs form...

Obstetrical ultrasound screening offer the possibility to assess the fetal thymus, which is located in the immediate proximity of the sternum, in the anterior superior mediastinum; the abnormal values of its measurements are high suggestive for a genetic disorder rather than a reflection of a pathological function of fetal immune system. Although there are several studies that report the existence of a significant correlation between fetal thymus involution and Trisomy 21, DiGeorge syndrome, intrauterine growth restriction, acute fetal distress, malnutrition or trauma, chorioamnionitis, also neonatal sepsis and acute respiratory distress syndrome, eventual correlation between an abnormal large fetal thymus and associate adverse pregnancy outcome has not been demonstrated. We present three cases of abnormal size of a fetal thymus lobe, detected by routine obstetrical ultrasonography after 30 weeks of gestation. The thymus had the ultrasound appearance of a hypo echoic avascular paracardiac supradiaphragmatic mass, movable synchronously with heart pulsations, with clear delimitation by the ventricular wall and the surrounding pulmonary tissue, measuring about 30/20 millimetres. All three pregnancies resulted in perfect health newborns, with normal involution of the thymus during the first six months of life and fitting in the normal range for age during childhood. We report this cases in order to emphasise the possibility of an abnormal large physiological development of the thymus, in the context of differential diagnosis with fetal cardiac tumours, thymic cysts, thyroid masses, teratomas, vascular anomalies and other pulmonary or mediastinal masses.Supporting information can be found in the online version of this abstract We report on a 39-year-old IIG IP, whose male fetus was sonographically diagnosed in the 25 week of the pregnancy with a smoothly limited 17x15x21 mm cyst in Douglas. Urinary bladder and intestine were well separated from the cystic findings. There were no abnormalities in the kidneys and the urinary tract. A connection to the spinal canal was not shown. The previous extended ultrasound diagnosis in the first and second trimesters revealed no abnormalities. By the time of birth, the findings in Douglas were slightly increased in size. The postpartum pediatric radiological ultrasound diagnostics showed that the cyst originated from the right sperm bladder. The observation has shown a complete spontaneous reconstruction of the cystic findings. Cysts of the seminal vesicle are more common in the childhood. In the prenatal phase, however, such cyst is a rarity.Supporting information can be found in the online version of this abstract A 38-year old woman, pregnancy 2, parity 1 was scanned at the first trimester in our hospital. Her obstetric history showed a delivery at term with low molecular weight heparin, because a previous thrombosis in her upper limb. The scan in the 12 weeks showed a reverse wave in ductus venosus, with normal uterine arteries, and a low risk for aneuploidy. During the 17 wee...