p16 status and high-risk human papilloma virus infection in squamous cell carcinoma of the nasal vestibule

Yamamura, Koji; Saito, Yuki; Kobayashi, K.; Mukai, Toshiyuki; Fukuoka, Osamu; Akashi, Ken; Yoshida, Masafumi; Ando, Mizuo; Yamasoba, Tatsuya

doi:10.1016/j.anl.2023.03.008

Auris Nasus Larynx

2023

DOI: 10.1016/j.anl.2023.03.008

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p16 status and high-risk human papilloma virus infection in squamous cell carcinoma of the nasal vestibule

Koji Yamamura¹,

Yuki Saito²,

K. Kobayashi³

et al.

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2024

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Cited by 2 publications

References 33 publications

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Human oncogenic viruses: a focus on head and neck carcinogenesis: a systematic review and meta-analysis

de Moraes,

dos Santos,

Pedroso

et al. 2024

Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology

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Human oncogenic viruses: a focus on head and neck carcinogenesis: a systematic review and meta-analysis

de Moraes,

dos Santos,

Pedroso

et al. 2024

Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology

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The Potential Role of the Microbiome in the Pathogenesis of Nasal Tumors: A Comprehensive Review

Loperfido,

Rizzo,

Fionda

et al. 2024

Medicina

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Cancers of the nose, and especially the nose vestibule, represent a significant challenge for clinicians due to their rarity, the intricate nature of surrounding vital structures, the nonspecific early symptoms, and the etiological factors that are not completely understood. Emerging research suggests that alterations in the nasal microbiome, also known as microbial dysbiosis, may contribute to the pathogenesis of those malignancies through mechanisms involving chronic inflammation, immune modulation, and cellular changes. The aims of this paper are to review the current literature covering the nasal microbiome’s role in carcinogenesis, particularly in the context of squamous cell carcinoma, and to explore how microbial dysbiosis might foster a pro-tumorigenic environment. It further discusses potential future directions for research and therapeutic approaches.

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p16 status and high-risk human papilloma virus infection in squamous cell carcinoma of the nasal vestibule

Cited by 2 publications

References 33 publications

Human oncogenic viruses: a focus on head and neck carcinogenesis: a systematic review and meta-analysis

Human oncogenic viruses: a focus on head and neck carcinogenesis: a systematic review and meta-analysis

The Potential Role of the Microbiome in the Pathogenesis of Nasal Tumors: A Comprehensive Review

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