P3.11 - Experimental and numerical evaluation of interdigitated electrode array for monitoring gaseous sterilization processes

Oberländer, Jan; Jildeh, Zaid B.; Kirchner, Patrick; Wendeler, Luisa; Bromm, Alexander; Iken, Heiko; Schöning, M. J.; Wagner, Peter; Keusgen, Michael

doi:10.5162/12dss2015/p3.11

Cited by 2 publications

(1 citation statement)

References 11 publications

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“…The additional T term is the thickness of the electrodes, which is 200 nm. As the fingers are completely covered by the coating, the dielectric constant between them is due to the dielectric constant of the coating [81]. Table 2 shows the dimensions of the four IDEs used and the estimated nominal capacitance, and Figure 17 shows the layout for the four IDEs.…”

Section: Ide Parametersmentioning

confidence: 99%

Molecularly Imprinted Electroimpedance Sensor for Detection of 8-isoprostane in Exhaled Breath Condensate

Gamero¹

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Development of low-cost, rapid response time capacitive sensors have a valuable role in the creation of point-of-care systems. A novel approach in the materials and application of Molecularly Imprinted Polymers was investigated for the detection of 8isoprostane in exhaled breath condensate. The detection method is based on the quantifiable capacitance change that occurs between two electrodes as the target molecule binds on the MIPs surface, which is detected through electrochemical impedance spectroscopy. This work focuses on the use of a generic polymer material for the sensing layer, as opposed to a traditional synthesized polymer material. PVA-SbQ was spun onto a custom IDE and then imprinted to detect 8-isoprostance. With aerosolized samples, the sensor was proven to detect a physiologically relevant concentration of 1 to 100 pg/mL. A fully integrated multiplexed system was then developed for point-of-care health monitoring.

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Section: Ide Parametersmentioning

confidence: 99%

Molecularly Imprinted Electroimpedance Sensor for Detection of 8-isoprostane in Exhaled Breath Condensate

Gamero¹

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An Enzyme-Based Interdigitated Electrode-Type Biosensor for Detecting Low Concentrations of H2O2 Vapor/Aerosol

Vahidpour

Alghazali

Akca³

et al. 2022

Chemosensors

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This work introduces a novel method for the detection of H2O2 vapor/aerosol of low concentrations, which is mainly applied in the sterilization of equipment in medical industry. Interdigitated electrode (IDE) structures have been fabricated by means of microfabrication techniques. A differential setup of IDEs was prepared, containing an active sensor element (active IDE) and a passive sensor element (passive IDE), where the former was immobilized with an enzymatic membrane of horseradish peroxidase that is selective towards H2O2. Changes in the IDEs’ capacitance values (active sensor element versus passive sensor element) under H2O2 vapor/aerosol atmosphere proved the detection in the concentration range up to 630 ppm with a fast response time (<60 s). The influence of relative humidity was also tested with regard to the sensor signal, showing no cross-sensitivity. The repeatability assessment of the IDE biosensors confirmed their stable capacitive signal in eight subsequent cycles of exposure to H2O2 vapor/aerosol. Room-temperature detection of H2O2 vapor/aerosol with such miniaturized biosensors will allow a future three-dimensional, flexible mapping of aseptic chambers and help to evaluate sterilization assurance in medical industry.

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P3.11 - Experimental and numerical evaluation of interdigitated electrode array for monitoring gaseous sterilization processes

Cited by 2 publications

References 11 publications

Molecularly Imprinted Electroimpedance Sensor for Detection of 8-isoprostane in Exhaled Breath Condensate

Molecularly Imprinted Electroimpedance Sensor for Detection of 8-isoprostane in Exhaled Breath Condensate

An Enzyme-Based Interdigitated Electrode-Type Biosensor for Detecting Low Concentrations of H2O2 Vapor/Aerosol

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