“…In children, P300 abnormalities have been associated with several pathologies including cognitive dysfunction (Finley et al 1985, Kaneko et al 1996, attention-deficit disorders (Holcomb et al 1985, Satterfield et al 1990, and dyslexia (Taylor and Keenan 1990). Moreover, the latency and amplitude of the P300 decrease and increase respectively with age, until adolescence, reflecting maturation processes in the CNS (Martin et al 1988, Polich et al 1990, Sangal et al 1998). Effects of prenatal exposure to PCBs and dioxins on the P300 have been addressed in the Yu Cheng, Taiwan cohort (Chen and Hsu 1994), consisting of children born to mothers that were accidentally exposed to high levels of PCBs and polychlorinated dibenzofurans.…”