P553 Elastic Fiber Accumulation Estimated by a Novel Automated Computational Analysis as a Significant Predicting Factor for the Development of Hepatocellular Carcinoma

Whole Slide Image Analysis System for Quantification of Liver Fibrosis

“…WSIs of liver biopsy specimens collected from 102 patients with hepatitis C were analyzed by our system [ 2 ]. The system successfully corrected the color of any WSI to that of the reference WSI and precisely extracted fine collagen and elastic fibers from portal and periportal areas ( Figure 1 ).…”