Paediatric cervical lymphadenopathy

Nolder, Abby R.

doi:10.1097/moo.0000000000000003

Cited by 25 publications

(26 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In addition, it is difficult to perform FNA in uncooperative children. Excision and histopathological evaluation of the lymph node remain the gold standard for the diagnosis of persistent cervical lymphadenopathy [3,6,7]. However, the question is when the surgeon should perform surgical excision in a patient with a swollen lymph node.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Predictive factors for malignancy in patients with persistent cervical lymphadenopathy

Çelenk

Gülşen

Baysal

et al. 2015

Eur Arch Otorhinolaryngol

View full text Add to dashboard Cite

The aim of this study was to identify clinical factors that can predict malignancy in patients with persistent cervical lymphadenopathy. This retrospective study included 575 patients with persistent cervical lymphadenopathy who underwent surgical excision. The patients were divided into two groups according to their ages: group 1 (≤18 years) and group 2 (>18 years). Multiple logistic regression models and univariate analysis were performed to determine the association between clinical factors and malignancy. Male gender [odds ratio (OR) 4.184, 95 % confidence interval (CI) 1.823-9.602, p = 0.001], increased age (OR 1.072, 95 % CI 1.001-1.148, p = 0.046), left-sided lesions (OR 3.423, 95 % CI 1.407-8.329, p = 0.007), and larger lymph node size (OR 1.445, 95 % CI 1.021-2.044, p = 0.038) were significantly associated with malignancy in group 1. Male gender (OR 3.761, 95 % CI 2.361-5.992, p = 0.001), increased age (OR 1.015, 95 % CI 1.003-1.027, p = 0.018), duration of the disease (OR 0.770, 95 % CI 0.668-0.888, p = 0.001), and the presence of B symptoms (OR 4.996, 95 % CI 2.862-8.721, p = 0.001) were significantly associated with malignancy in group 2. The sensitivity and specificity of the models were 84 and 61.5 % for group 1 and 77.9 and 67.9 % for group 2, respectively. Increasing age and male gender were found to be associated with malignancy in all age groups. Larger lymph node size and left-sided lymphadenopathy were significant predictors of malignancy in children. Presence of B symptoms was found to be associated with malignancy in adults. Our results indicated that increasing duration of lymphadenopathy and the presence of bilaterality render the lymph node more likely to be benign in adults. No significant association was found between the involved neck site and malignancy for all age groups.

show abstract

Section: Introductionmentioning

confidence: 99%

“…Although the majority of the cervical lymphadenopathies are benign, a wide variety of malignant and systemic pathologies may cause such a clinical situation [3]. Accordingly, initial evaluation of enlarged cervical lymph nodes is extremely important.…”

Section: Introductionmentioning

confidence: 99%

Predictive factors for malignancy in patients with persistent cervical lymphadenopathy

Çelenk

Gülşen

Baysal

et al. 2015

Eur Arch Otorhinolaryngol

View full text Add to dashboard Cite

show abstract

“…Bu nedenle birçok faktör gözden geçirilerek açık biyopsi kararı alınır. [18,19] Multidisipliner değerlendirmelerin biyopsi gerekliliğini azalttığı bazı çalışmalarda gösterilmiştir. [20] Çocuk hekiminden radyologdan, patologdan ve kulak burun boğaz uzmanından oluşan ekibin açık biyopsi öncesi hastayı değerlendirmesi gerekir.…”

Section: Açık Biyopsi Endikasyonlarıunclassified

“…[21] Hasta sevk edilen büyük merkezlerde ve pediatrik hemato-onkoloji merkezlerinde açık biyopsi oranları sıra-sıyla %28 ile %38 arasında değişirken sonuçları malignite gelen biyopsi oranları sırasıyla %23 ile %30'dur. [8,22] Hangi durumlarda açık biyopsiyi düşünmemiz gerektiği şu faktörlerle özetlenebilir: [6,18,19] • Malignite şüphesi • Antibiyotik tedavisine rağmen dört ile altı haftadan uzun süredir devam eden tanı konulamayan lenfadenopati • Lenfadenopati boyutunun iki haftada artış gös-termesi • İki santimetreden büyük lenfadenopati • Supraklaviküler lenfadenopati • Anormal akciğer grafisi • Sistemik belirtiler/malignite düşündüren semptomlar: kilo kaybı hepatosplenomegali, ateş ve eklem ağrıları.…”

Section: Açık Biyopsi Endikasyonlarıunclassified

Approach to pediatric cervical lymphadenopathy

Yazıcı¹

2015

KBB Uygulamaları

View full text Add to dashboard Cite

ÖZServikal lenfadenopati pediatrik nüfusta yaygın olarak görülür; sağlıklı çocukların yaklaşık %38 ila %45'inde ele gelen lenfadenopati bulunabilir. Esasen, doğru bir insidans vermek zordur çünkü viral üst solunum yolu hastalıklarından sonra görülüp kendini sınırlayan bir patolojidir. Ayırıcı tanısında birçok hastalık olabileceği için ayrıntılı öykü ve fizik muayene doğru tanıyı koymaya yardımcıdır. En sık rastlanan neden enfeksiyondur.Anahtar sözcükler: Servikal; lenfadenopati; pediatrik. ABSTR ACTCervical lymphadenopathy is common in the pediatric population; palpable lymphadenopathy may be present in approximately 38 to 45% of healthy children. In fact, it is difficult to give a true incidence since it is a pathology that is seen after viral upper respiratory diseases and limits itself. Detailed history and physical examination assist in establishing a correct diagnosis since many diseases may be involved in its differential diagnosis. The most common cause is infection.

show abstract

“…Lenf düğümleri vücudumuzda yaygın olarak bulunan, lenf kanalikülleri boyunca yerleşmiş küçük duraklardır. En fazla intermamiller hattın üzerinde, baş ve boyun bölgesinde yer alır (24). Vücudumuzda toplam 300-600 arasında lenf bezi vardır ve bunların yaklaşık yarısı baş-boyun bölgesinde yer almaktadır.…”

Section: Introductionunclassified

Çocukluk Çağinda Lenfadenopati̇ye Yaklaşim

2015

View full text Add to dashboard Cite

Lymphadenopathy is a common symptom in children. Although, the most common causes are infection and autoimmune diseases, most dangerous are malignancies. It can be local or generalized. In local lymphadenopaties infections are prominent causes but in generalized forms systemic diseases should be considered. The rate of malignancy is 1-3 % and lymphomas are most common. Ultrasonography can be helpful with some of the findings to the physician for differential diagnosis and malignancy. If diagnosis could not be confirmed or malignancy is suspected, biopsy is essential.

show abstract

Paediatric cervical lymphadenopathy

Cited by 25 publications

References 19 publications

Predictive factors for malignancy in patients with persistent cervical lymphadenopathy

Predictive factors for malignancy in patients with persistent cervical lymphadenopathy

Approach to pediatric cervical lymphadenopathy

Çocukluk Çağinda Lenfadenopati̇ye Yaklaşim

Contact Info

Product

Resources

About